实用医学杂志 ›› 2021, Vol. 37 ›› Issue (14): 1820-1823.doi: 10.3969/j.issn.1006⁃5725.2021.14.009

• 临床研究 • 上一篇    下一篇

多因素分析足踝部软组织肿瘤和骨肿瘤的临床病理特征及生存率

景青玲   

  1. 青海大学附属医院创伤骨科(西宁 810001)

  • 出版日期:2021-07-25 发布日期:2021-07-25
  • 基金资助:

    青海省医药卫生科技项目指导性计划课题(编号:2018⁃wjzdx⁃46)

Multivariate analysis of clinicopathological features of soft tissue tumors and bone tumors in foot and an⁃ kle 

JING Qingling.    

  1. Orthopaedic TraumaQinghai University Affiliated HospitalXining 810001China 
  • Online:2021-07-25 Published:2021-07-25

摘要:

目的 研究足踝部软组织肿瘤与骨肿瘤患者的临床预后和病理特征的分析。方法 选取 我院收治的 120 例足踝部软组织肿瘤和骨肿瘤患者,分析研究对象的临床病理特征和影响临床预后的相 关因素。结果 术后随访获得 69 例,软组织恶性肿瘤 50 例,骨恶性肿瘤 19 例;骨恶性肿瘤患者 1 年生存率为 75.36%,明显高于 3 年 55.07%和 5 年 55.07%;单因素分析发现 69 例足踝部恶性肿瘤患者因辅助治疗、 功能状况和肿瘤大小影响了5年生存率(< 0.05),但性别、年龄、手术方法、组织类型和发病部位等对患者预 后无明显影响(> 0.05);多因素分析发现肿瘤大小和功能状况是影响69例足踝部恶性肿瘤患者生存率的独 立危险因素(HR = 7.251、6.194,P<0.005)。结论 足踝部良性软组织肿瘤多以血管瘤常见,而恶性肿瘤 多以滑膜肉瘤常见;肿瘤大小和功能状况是影响足踝部恶性肿瘤患者预后差的主要原因,且> 5 cm 的恶 性肿瘤患者临床预后更差。

关键词:

足踝部,  , 软组织肿瘤,  , 骨肿瘤

Abstract:

Objective To study the clinical prognosis and pathological characteristics of patients with soft tissue tumors and bone tumors in the foot and ankle. Methods We selected 120 patients with foot and ankle soft tissue tumors and bone tumors admitted to our hospital,and analyzed the clinical pathological characteristics of the subjects and related factors affecting clinical prognosis. Results 69 cases were followed up after operation,50 cases of soft tissue malignant tumors,19 cases of bone malignant tumors. The 1⁃year survival rate of patients with bone malignant tumors was 75.36%,which was significantly higher than the 3⁃year of 55.07% and 5⁃year of 55.07%. Univariate analysis found the 5⁃year survival rate of 69 patients with foot and ankle malignant tumors was affected by adjuvant treatment,functional status and tumor size(P < 0.05),but gender,age,surgical method,tissue type and location of tumor had no significant impact on the prognosis of patients(P > 0.05);Multivariate analysis found that tumor size and functional status were independent risk factors affecting the survival rate of 69 patients with foot and ankle malignant tumors(HR = 7.251,6.194,P = 0.005). Conclusion Benign soft tissue tumors of the foot and ankle are mostly hemangioma,while malignant tumors are mostly synovial sarcoma;tumor size and functional status are the main factors for the poor prognosis of patients with malignant tumors of the foot and ankle ,and patients with malignant tumors > 5 cm have a worse clinical prognosis.

Key words: foot and ankle,  , soft tissue tumors,  , bone tumors