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Study on the association between gaseous pollutants and cardiovascular disease hospitalization， hospitalization costs， and hospitalization days in seven cities of Guangdong province
Received date: 2024-10-21
Online published: 2025-01-26
Objective To investigate the impact of gaseous pollutants （SO2， NO2， CO， O3） on hospital admissions， hospitalization costs， and length of stay for cardiovascular diseases in seven cities of Guangdong Province. Methods A total of 2，010，905 patients with cardiovascular diseases from seven cities in Guangdong Province between January 2017 and December 2019 were included. Demographic characteristics and hospitalization data for cardiovascular disease inpatients were obtained from the Guangdong Province Electronic Healthcare Information System. Daily exposure concentrations of SO2， NO2， CO and O3 were extracted from the China High?Air?Pollution Dataset. The impact of air pollutants on cardiovascular diseases in the seven cities of Guangdong Province was estimated using a multi?step time?series analysis. Results SO2， NO2， and CO concentrations on the day of admission （lag0） were positively associated with the risk of cardiovascular admissions， hospitalization costs， and length of stay， with NO2 exhibiting the strongest effect. Additionally， there was a lagged negative impact of NO2 and CO， while O3 concentrations were inversely correlated with the number of cardiovascular admissions， hospitalization costs， and length of stay over the lag0?7 period. Conclusions Short?term exposures to SO2， NO2， and CO are likely positively associated with the disease burden in CVD patients. Furthermore， given the more substantial adverse effects of NO2， enhanced monitoring of NO2 remains essential. However， as this study is retrospective， additional research is warranted.
Key words： air pollution; gaseous pollutants; cardiovascular disease; disease burden
Xingyu CHEN , Ying XIAO , Hualiang LIN , Lawrence Lam. . Study on the association between gaseous pollutants and cardiovascular disease hospitalization， hospitalization costs， and hospitalization days in seven cities of Guangdong province[J]. The Journal of Practical Medicine, 2025 , 41(2) : 278 -287 . DOI: 10.3969/j.issn.1006-5725.2025.02.019
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