Clinical Advances

Applications and advances of lipidomics in kidney disease

  • Jiahui WANG ,
  • Ke ZHENG ,
  • Xuemei LI
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  • Department of Nephrology,Peking Union Medical College Hospital,Chinese Academy of Medical Sciences,Beijing 100730,China

Received date: 2024-06-05

  Online published: 2025-01-14

Abstract

Kidney disease constitutes a significant global public health issue, with its associated healthcare burden escalating annually. Lipid metabolism disorders play a crucial role in the onset and progression of various kidney diseases. Given the diversity of lipid species and the complexity of metabolic pathways, traditional research methods often fall short in fully elucidating the intricate roles of lipids in kidney diseases. In this context, lipidomics, the systematic analysis of lipid molecules and their metabolic alterations in biological samples, emerges as a powerful tool with unique research value and clinical potential. This review summarizes the latest findings in lipidomics across various kidney diseases and discusses the challenges encountered in clinical application and future research directions.

Cite this article

Jiahui WANG , Ke ZHENG , Xuemei LI . Applications and advances of lipidomics in kidney disease[J]. The Journal of Practical Medicine, 2025 , 41(1) : 1 -6 . DOI: 10.3969/j.issn.1006-5725.2025.01.001

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