The Journal of Practical Medicine >

2024 , Vol. 40 >Issue 15: 2172 - 2176

DOI: https://doi.org/10.3969/j.issn.1006-5725.2024.15.022

Reviews

Advances in the role of mitochondrial respiratory chain enzyme complexes in myocardial ischemia-reperfusion injury

  • Zhu LI ,
  • Yan WANG ,
  • Wenjing ZHOU ,
  • Haiying. WANG
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  • *.Department of Anesthesiology，Affiliated Hospital of Zunyi Medical University，Zunyi 563003，China

Received date: 2024-03-06

  Online published: 2024-07-30

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Abstract

Myocardial ischemia reperfusion injury （MIRI） is a common cardiovascular complications， which is a major problem for many clinical scholars. To improve the prognosis of MIRI， many scholars have devoted to the research of its mechanism， and founded that mitochondria are closely related to the occurrence of MIRI， where the function of mitochondrial respiratory chain enzyme complex is impaired， and energy metabolism disorders play a key role in the process of MIRI. The aim of this review is to describe the changes of mitochondrial respiratory chain enzyme complex in MIRI and its effect on MIRI， and to provide a basis for finding new and effective therapeutic targets for MIRI.

Key words： myocardial ischemia reperfusion injury; mitochondrial enzyme complexes; mitochondrial respiratory chain

Cite this article

Zhu LI , Yan WANG , Wenjing ZHOU , Haiying. WANG . Advances in the role of mitochondrial respiratory chain enzyme complexes in myocardial ischemia-reperfusion injury[J]. The Journal of Practical Medicine, 2024 , 40(15) : 2172 -2176 . DOI: 10.3969/j.issn.1006-5725.2024.15.022

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