The Journal of Practical Medicine ›› 2024, Vol. 40 ›› Issue (15): 2172-2176.doi: 10.3969/j.issn.1006-5725.2024.15.022

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Advances in the role of mitochondrial respiratory chain enzyme complexes in myocardial ischemia-reperfusion injury

Zhu LI1,Yan WANG1,Wenjing ZHOU2,Haiying. WANG1()   

  1. *.Department of Anesthesiology,Affiliated Hospital of Zunyi Medical University,Zunyi 563003,China
  • Received:2024-03-06 Online:2024-08-10 Published:2024-07-30
  • Contact: Haiying. WANG E-mail:8901@163.com;wanghaiting-8901@163.com

Abstract:

Myocardial ischemia reperfusion injury (MIRI) is a common cardiovascular complications, which is a major problem for many clinical scholars. To improve the prognosis of MIRI, many scholars have devoted to the research of its mechanism, and founded that mitochondria are closely related to the occurrence of MIRI, where the function of mitochondrial respiratory chain enzyme complex is impaired, and energy metabolism disorders play a key role in the process of MIRI. The aim of this review is to describe the changes of mitochondrial respiratory chain enzyme complex in MIRI and its effect on MIRI, and to provide a basis for finding new and effective therapeutic targets for MIRI.

Key words: myocardial ischemia reperfusion injury, mitochondrial enzyme complexes, mitochondrial respiratory chain

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