The Journal of Practical Medicine >

2023 , Vol. 39 >Issue 22: 2989 - 2993

DOI: https://doi.org/10.3969/j.issn.1006-5725.2023.22.023

Investigations

The molecular characteristics of ParechovirusA in patients with acute gastroenteritis in Sanya during 2019-2020

  • Liju HUANG ,
  • Yongzhi LI ,
  • Huan HE ,
  • Tingli SHI ,
  • Caiyun CHEN ,
  • Liting ZHENG ,
  • Minyi LIANG ,
  • Jiaqi CHEN ,
  • Qing. CHEN
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  • *.Sanya Center for Disease Control and Prevention，Sanya 572002，China

Received date: 2023-09-19

  Online published: 2023-12-11

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Abstract

Objective To invesigate the prevalence and genetic characteristics of ParechovirusA （PeV-A） in tropical areas. Methods Acute diarrhea disease surveillance was conducted at Sanya Central Hospital between January 2019 and August 2020. Patient data and fecal specimens were collected. PeV-A was detected by nested RT-PCR， and phylogenetic analyses of specific gene sequences were performed. Results Two hundred and sixty-seven patients with acute gastroenteritis were included in this study. The PeV-A detection rate was 3.37% （9/267）， and three PeV-A genotypes （HPeV1， HPeV3， and HPeV5） were detectable， which were most closely related to the reference strains from either Beijing or Hong Kong. The HPeV-positive patients were predominantly young children under the age of 2 years. The detection rate of PeV-A was higher in summer and winter （May to August and December to February， respectively）. Patients with PeV-A-positive diarrhea had a higher proportion of respiratory infections， abdominal pain， vomiting， and fever than those with PeV-A-negative diarrhea. Rotavirus and norovirus were the most common viruses co-infected with PeV-A in patients with acute gastroenteritis. Conclusions PeV-A is an important pathogen of acute gastroenteritis in Sanya， and its prevalent genotypes are similar to those reported in other regions of China.

Key words： parechovirus A; acute gastroenteritis; epidemiology

Cite this article

Liju HUANG , Yongzhi LI , Huan HE , Tingli SHI , Caiyun CHEN , Liting ZHENG , Minyi LIANG , Jiaqi CHEN , Qing. CHEN . The molecular characteristics of ParechovirusA in patients with acute gastroenteritis in Sanya during 2019-2020[J]. The Journal of Practical Medicine, 2023 , 39(22) : 2989 -2993 . DOI: 10.3969/j.issn.1006-5725.2023.22.023

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