Reviews

Experimental research progress of 3D printing bionic scaffold in repairing of spinal cord injury

Expand
  • Department of Orthopaedics,the First Affiliated Hospital of Nan⁃ chang University,Nanchang 330006,China;*The Fourth Clinical Medical College of Nanchang University,Nan⁃ chang 330100,China

Online published: 2022-11-25

Abstract

The new biomimetic spinal cord scaffold manufactured by 3D printing has good biocompatibility and mechanical properties,which can effectively improve the microenvironment disorder and glial scar problems after spinal cord injury(SCI). By combining specific nerve cells,the repair of SCI can also be more targeted and specific. In recent years,many new spinal scaffolds and their corresponding treatment methods have been devel⁃ oped,including new scaffolds based on collagen and improved by mixing other materials,new synthetic materials spinal scaffolds and new treatment ideas of nerve cells modified by specific factors on scaffolds. The feasibility of the treatment methods has been verified through animal experiments,which provides a new direction for the repair and treatment of SCI. This article reviews the experimental research progress of 3D printed biomimetic scaffolds in the repair of spinal cord injury.

Cite this article

ZHANG Hao, ZHANG Yu, XIAO Shining, LIU Jiaming. .

Experimental research progress of 3D printing bionic scaffold in repairing of spinal cord injury

[J]. The Journal of Practical Medicine, 2022 , 38(22) : 2868 -2873 . DOI: 10.3969/j.issn.1006⁃5725.2022.22.019

Options
Outlines

/