Abstract:

Chronic cough （CC） is a common respiratory disorders， with prevalence rates as high as 10% ~ 20%. The burden of CC can be severe， as patients with CC experience substantial physical effects （e.g.， stress urinary incontinence， sleep disturbance， and chest pain）， psychological consequences （e.g.， frustration， anxiety， and depression）， and social impairments （e.g.， social distress/isolation and reduced quality of life）. As a result， CC is a frustrating conundrum for patients and clinicians. In this paper， combined with the new concepts of domestic and foreign literature， we expound the concept of CC， epidemiology， pathogenesis， etiological structure， clinical manifestations and auxiliary examination， diagnosis and differential diagnosis， treatment， and future prospects， etc.， for peer reference and learn from， so as to promote more in-depth related clinical research.

Key words: chronic cough, cough hypersensitivity syndrome, diagnosis, therapy, research advancement, new concept