胆汁酸在酒精性肝病中的作用研究进展

doi:10.3969/j.issn.1006-5725.2024.15.025

Abstract

Abstract:

Alcoholic liver disease is liver disease caused by heavy and/or chronic alcohol consumption. Bile acids are synthesized in the liver and regulate the body through liver-intestinal circulation. Many studies have shown that bile acid is closely related to alcoholic liver disease. Alcohol intake can cause liver damage by affecting bile acid synthesis， hepato-enteric circulation and intestinal flora. This article summarizes the mechanism of action of bile acids in alcoholic liver disease and the current research status of improving alcoholic liver disease based on bile acid regulation， in order to provide new ideas for future research on the prevention and treatment of alcoholic liver disease.

Key words: alcoholic liver disease, bile acid, intestinal flora, enterohepatic circulation

CLC Number:

R575

Nan LI,Xue ZHAO, A′nali,Heran LIANG,Na. GE. Research progress on the role of bile acids in alcoholic liver disease[J]. The Journal of Practical Medicine, 2024, 40(15): 2187-2193.

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