Abstract:

Objective To analyze the clinical efficacy and safety of CT⁃guided thoracic drainage microtu⁃ bule for patients of emphysema complicated with giant pulmonary bullae. Methods A total of 74 patients of emphysema with giant pulmonary bullae into our hospitalwerechosed. As the control group，30 patients underwent surgical thoracoscopic surgery，while the observation group included 44 patients who underwent CT⁃guided place⁃ ment of thoracic drainage microtubules. The operation indexes between the two groups were compared，including operation time，bleeding volume，incision infection，postoperative drainage time，postoperative stay ⁃in hospital days，tube time and lung re⁃expansion time，pain visual analogue scale（VAS）score 1 d，3 d and 7 d after opera⁃ tion，disappearance time and recurrence rate of giant pulmonary bullae. The levels of serum inflammatoryfactors C⁃reactive protein（CRP）and interleukin⁃6（IL⁃6）before and 2 d after operation，as well as arterial partial pressure （PaO2），peripheral oxygen saturation（SaO2）and forced expiratory volume in the first second（FEV1）before and 1 d after operation. Results The observation group′s operation time，hospital stay days，and lung re⁃expansion time were shorter than the control group′s，tube time was longer，bleeding volume was less，pain VAS scores 1 d，3 d after operation were lower than the control group，serum CRP and IL⁃6 levels were lower，and postoperative PaO2， SaO2，and FEV1 were higher（P < 0.05）. Conclusion CT ⁃ guided thoracic drainage microtubule placement improves clinical efficacy and safety in emphysema with giant pulmonary bullae.It causes less trauma，less pain and inflammation，and improves pulmonary function more than thoracoscopic resection.

Key words:

emphysema, pulmonary bullae, thoracic drainage microtubule, thoracoscopy surgery, pulmonary function