自体脂肪移植治疗瘢痕的研究进展

doi:10.3969/j.issn.1006-5725.2025.09.022

Abstract

Abstract:

Scarring is a key issue in plastic surgery research and there are limitations in the clinical outcomes of existing scar treatments. Autologous fat grafting is a new method that has been clinically proven to be effective in the treatment of pathological scarring. Autologous fat grafts contain adipose-derived mesenchymal stem cells and a variety of active factors that can effectively improve the appearance， texture and local symptoms of keloid scars through the mechanisms of immunomodulation of the inflammatory response， pro-angiogenesis， pro-cellular differentiation， extracellular matrix remodelling and resistance to oxidative stress damage， etc. It has the advantages of fewer complications and better therapeutic effect， and is a brand new field of keloid scar， which provides a new therapeutic direction for the keloid scar. The new field of scar treatment provides a new direction for scar treatment. The application and mechanism of autologous fat grafting in keloid scar is now reviewed， with the aim of providing a theoretical basis for the treatment of keloid scar and summarising the progress of its application in keloid scar treatment.

Key words: scar, autologous fat grafting, adipose-derived stem cells, regenerative medicine

CLC Number:

R619+.6

Xifeng AN,Xuan LIAO,Hongwei LIU. Progress in autologous fat grafting for scar treatment[J]. The Journal of Practical Medicine, 2025, 41(9): 1425-1432.

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