The Journal of Practical Medicine ›› 2025, Vol. 41 ›› Issue (12): 1867-1872.doi: 10.3969/j.issn.1006-5725.2025.12.014
• Clinical Research • Previous Articles
Received:
2025-02-10
Online:
2025-06-25
Published:
2025-07-02
Contact:
Yunting FU
E-mail:fytmiao@163.com
CLC Number:
Li ZHANG,Yunting FU. The correlation between serum P⁃Tau181, GGT, SIRT1 and sleep disorders in patients with cerebral small vessel disease[J]. The Journal of Practical Medicine, 2025, 41(12): 1867-1872.
Tab.1
Comparison of baseline data between two groups"
因素 | 睡眠障碍组 (n = 52) | 睡眠正常组 (n = 104) | P值 | |
---|---|---|---|---|
年龄(x ± s)/岁 | 62.53 ± 4.71 | 61.09 ± 5.27 | 1.665 | 0.098 |
性别 | 0.120 | 0.729 | ||
男 | 32(61.54) | 61(58.65) | ||
女 | 20(38.46) | 43(41.35) | ||
合并症 | ||||
糖尿病 | 16(30.77) | 27(25.96) | 0.401 | 0.526 |
高血压 | 22(42.31) | 29(27.88) | 3.277 | 0.070 |
慢性支气管炎 | 14(26.92) | 17(16.35) | 2.436 | 0.119 |
脑小血管病类型 | 1.082 | 0.781 | ||
腔隙性脑梗死 | 21(40.38) | 50(48.08) | ||
脑微出血 | 8(15.38) | 14(13.46) | ||
脑微梗死 | 22(42.31) | 37(35.58) | ||
脑萎缩 | 1(1.92) | 3(2.88) | ||
GDS评分(x ± s)/分 | 3.19 ± 0.72 | 3.04 ± 0.65 | 1.310 | 0.192 |
Tab.3
Comparison of two conventional laboratory indicators"
组别 | 例数 | TC/(mmol/L) | TG/(mmol/L) | LDL-C/(mmol/L) | FBG/(mmol/L) | Hcy/(μmol/L) | Aβ1-42/(pg/mL) |
---|---|---|---|---|---|---|---|
睡眠障碍组 | 52 | 4.85 ± 0.82 | 1.46 ± 0.32 | 2.76 ± 0.41 | 4.72 ± 1.36 | 12.03 ± 1.67 | 39.64 ± 4.15 |
睡眠正常组 | 104 | 4.63 ± 0.79 | 1.41 ± 0.39 | 2.70 ± 0.45 | 4.51 ± 1.09 | 11.95 ± 1.25 | 38.41 ± 3.92 |
t值 | 1.619 | 0.799 | 0.808 | 1.042 | 0.336 | 1.820 | |
P值 | 0.107 | 0.425 | 0.420 | 0.299 | 0.738 | 0.071 |
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