Abstract:

Objective To compare the effects of injection needle scalpel，small needle scalpel and sodi⁃ um hyaluronate intraarticular injection in the treatment of knee osteoarthritis（KOA）. Methods One hundred and fifty⁃six patients with KOA were randomly divided into three groups in equal number：groups A，B and C（n = 52）， treated with small needle knife treatment，intraluminal injection of sodium hyaluronate and injection needle scalpel once a week for three consecutive times，respectively. The Visual Analogue Scale（VAS）and Lysholm Knee Scale （LKS）were used for the evaluation at the time points：before operation，3 days，10 days，20 days，1 month，3 months and 6 months after operation. The knee joint range of motion（ROM）was measured before treatment and 1 month after treatment. The curative effect was evaluated 1 month after treatment. Results （1）The VAS pain scores in group C were significantly lower than those in groups A and B（both P < 0.001）. The LKS score in group C was significantly higher than that of groups A and B（both P < 0.001）. The range of motion of knee joint in group C was greater than that of groups A and B（both P < 0.001）. The curative effect of group C was better than that of group A（P = 0.011）and group B（P = 0.009）. The total effective rate of group C was higher than that of group A （P = 0.006）and group B（P = 0.013）.（2）At days 3，10，20，and 1 month after treatment，the VAS score of group B was lower than that of group A（P < 0.001）；The LKS score in group B was higher than that in group A （P < 0.001，< 0.001，< 0.001，= 0.005 for different time points）. Three months after treatment，there was no significant difference in VAS score and LKS score between group A and group B（P = 0.302，P = 0.469）. Six months after treatment，the VAS scores in group A were lower than those in group B（both P < 0.001）. The LKS score of group A was higher than that of group B（P < 0.001）. The total effective rate of group A was higher than that of group B（χ2 = 8.409，P = 0.015）. Conclusion Injection needle scalpel is better than small needle scalpeland sodium hyaluronate intraluminal injection in treating KOA patients at the early and medium stage. The total effectiveness rate of small needle scalpel is higher than that of sodium hyaluronate intraluminal injection. Sodium hyaluronate intraluminal injection takes effect faster than small needle scalpel does. The efficacy of small needle scalpel lasts longer than sodium hyaluronate intraluminal injection does.

Key words:

knee osteoarthritis, injection needle scalpel, small needle scalpel, sodium hyaluro? nate, intraarticular injection, joint function