Objective To analize the influencing factors of diagnosis delay of patients with pulmonary tuberculosis in this area，and further to provide a scientific basis for improving continuously regional tuberculosis control plans and measures. Methods The reported information of new pulmonary tuberculosis cases in Yingde City，Guangdong from 2010⁃2020 was collected and abstracted from Tuberculosis Information Management System of China Information System for Disease Control and Prevention. Furthermore，the general levels trend and influencing factors（including gender，age，residence，medical institution of providing diagnosis，etc）of diagnosis delay， which defined as more than 28 days from the date of symptom onset to the date of diagnosis，were retrospectively analyzed during eleven years. Results （1）The total number of new pulmonary tuberculosis cases registered was 11 973 cases，and diagnosis delay occurred in 3 189 cases（accounting for 26.63%）. And the median time of diagnosis delay was 17 days，which this time was calculated from the 29th day of symptom start date to the clear diagnosis date.（2）The ratio of diagnosis delay were about 30% in 2010，2011 and 2020 and that of the other years were fluctuating between 22.35% ~ 26.65%. The trend of median time of diagnosis delay was increased year by year in 2010⁃2014 and median time of diagnosis delay jumped to a peak of 33 days in 2014. Fortunately，the trend in subsequent 6 years was a general decline and the minimum of median time of diagnosis delay was 9 days in 2018.（3）The ratio of diagnosis delay in ≥ 60 years group was 22.61% and significantly lower than other ages groups （P = 0.000）. The ratio of diagnosis delay of cases living in district，suburban，rural increased in turn and presented significant difference（P = 0.000）among them. But，there was no significant difference between male and female （P = 0.462）.（4）The median time of diagnosis delay were 17 days and 16 days for male and female and 10，13， 18 and 20 days for cases of < 18，18 ~ 44，45 ~ 59 and ≥ 60 age groups respectively. It were 19，17，16 days for cases from suburbs，rural and urban and 20，15，12 and 8 days for cases visiting to comprehensive medical institu⁃ tions，town health center and prison hospitals，chronic disease prevention hospitals respectively. Conclusion The overall situation of diagnosis delay for pulmonary tuberculosis have obtained continuous improvement in Yingde City，Guangdong. However its major influencing factors，including age，residence，medical institution，etc，must be payed more attention and suitable new strategies and measures must be formulated and fulfilled.