The Journal of Practical Medicine ›› 2022, Vol. 38 ›› Issue (20): 2630-2634.doi: 10.3969/j.issn.1006⁃5725.2022.20.022

• Reviews • Previous Articles    

Research Progress of Mesenchymal Stem cells in the treatment of severe burn ⁃ induced Hepatic injury

LIN Hui，PANG Rongqing.   

  1. Stem Cells and Immune Cells Biomedical Techniques Integrated Engineering Laboratory of State and Regions，Cell Therapy Technology Transfer Medical Key Laboratory of Yunnan Province，Kunming Key Laboratory of Stem Cell and Regenerative Medicine，Basic Medical Laboratory，920 Hospital of Joint Logistics Sup⁃ port Force of Chinese PLA，Yunnan Province，Kunming 650032，China

  • Online:2022-10-25 Published:2022-10-24

Abstract:

Burn is a post⁃traumatic inflammatory disease. Multiple organ failure is the main cause of death after burn. Excessive systemic and local inflammation directly leads to terminal organ injury. Liver is the largest metabolic and detoxification organ of the human body，and it is easy to be attacked by endotoxin. The deterioration of liver function will lead to increased morbidity and mortality of burn patients. Therefore，the repair of hepatic injury after severe burn is of great significance. Although progress has been made in the clinical management of burns， there are still limitations in the treatment of severe burns. In recent years，Mesenchymal stem cells（MSCs）have shown great promise in tissue repair. In this review，we will focus on the role of MSCs in severe burn⁃induced hepatic injury.

Key words:

mesenchymal stem cells, burn, liver