The Journal of Practical Medicine ›› 2022, Vol. 38 ›› Issue (11): 1309-1313.doi: 10.3969/j.issn.1006⁃5725.2022.11.002

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Application and research progress of Tirofiban in the treatment of acute ischemic stroke

SHI Heng*，HOU Miaomiao，SUN Bo，LIU Xiaolei，LI Xinyi.   

  1. Third Hospital of Shanxi Medical University，Shanxi Bethune Hospi⁃ tal，Shanxi Academy of Medical Sciences，Tongji Shanxi Hospital，Taiyuan 030032，China；*Third Clinical Medi⁃ cal College of Shanxi Medical University，Taiyuan 030000，China 

  • Online:2022-06-10 Published:2022-06-10
  • Contact: LI Xinyi E⁃mail：xinyili2003@163.com

Abstract:

Acute ischemic stroke is a clinical syndrome manifesting nerve function impairment caused by brain ischemia and hypoxia. Antiplatelet therapy is the basis for the prevention and treatment of acute cerebral infarction. As a novel antiplatelet drug and inhibitor of GP IIb/IIIa receptor，tirofiban has been basically mature in the treatment of cardiovascular diseases. However，application of tirofiban for cerebrovascular diseases is still in the exploratory stage，and the administration routes，dosage and safety are still controversial. This paper reviews the application and research progress of tirofiban in the treatment of acute ischemic stroke.

Key words:

Tirofiban, acute ischemic stroke, antiplatelet, intravenous thrombolysis, mechanical thrombectomy