Abstract:

Objective To analyze the prevalence of pregnancy with diabetes mellitus and provide evidence for the prevention and control of pregnancy with diabetes mellitus in Guangdong Province. Methods Based on an obstetric quality report from 2 440 medical institutions in 21 cities of Guangdong province from 2016 to 2020，we analyzed the current status of prevalence of gestational diabetes mellitus in Guangdong and the relationship between gestational diabetes mellitus and adverse pregnancy outcomes including cesarean section，premature infants， perinatal death. Results During the study period，a total of 8 553 069 pregnant women were monitored，and 639 637 of them were reported as having pregnancy with diabetes，with a prevalence rate of 7.48% in Guangdong. The prevalence of pregnancy with diabetes mellitus from 2016 to 2020 showed a trend of linear growth，and it was statistically significant（χ2 = 35 738.01，P < 0.001）. Among all the cities，Foshan had the highest prevalence rate of 14.20 %，while Jieyang had the lowest rate of 0.45%；Division by administrative regions，the Pearl River Triangle area had the highest rate of 10.53%，whereas Yuexi had the lowest rate of 2.84%. There were significant differences in the prevalence rate among different administrative regions（P < 0.05）. Division by medical institutions，the third⁃ level hospitals had the highest rate of 11.08%，while the first⁃level hospitals had the lowest rate of 2.22%. There were significant differences in the prevalence rate among different medical institutions（P < 0.05）. In the correlation analysis on pregnancy with diabetes mellitus and adverse pregnancy outcomes，pregnancy complicated with diabetes was positively correlated with Cesarean section，premature infants and perinatal death（P < 0.05）. Conclusions During the period of 2016 to 2020，the prevalence of pregnancy with diabetes in Guangdong province increased significantly，with a significant regional difference. The disorder was positively correlated with adverse pregnancy outcomes.

Key words:

pregnancy with diabetes mellitus, prevalence, epidemiological characteristics