Abstract:

Objective To compare the efficacy of unilateral and bilateral pedicle screw fixation combined with OLIF in the treatment of lumbar degenerative diseases. Methods A total of 86 patients with lumbar degenerative diseases were treated with OLIF combined with pedicle screw fixation in our Hospital from July 2017 to November 2019. 53 cases were treated with OLIF combined with unilateral pedicle screw fixation，and 33 patients in bilateral pedicle screw fixation group. The clinical effects of the two groups were evaluated by low back pain VAS and ODI. The damage of paraspinal muscles was evaluated by paraspinal electromyography，and the height of intervertebral space was measured by imaging. Interbody fusion was evaluated and related complications were analyzed. Results The VAS score and ODI index of low back pain in the UPS group were lower than those in the BPS group at different time after operation. The operation time，intraoperative blood loss，hospitalization cost and the incidence of paraspinal muscle denervation in the UPS group were significantly lower than those in the BPS group（P < 0.05）. There was no significant difference in the average hospital stay，incidence of complications and fusion rate between the two groups（P > 0.05）. Conclusion Unilateral pedicle screw fixation combined with OLIF via Wiltse approach has a satisfactory clinical effect in the treatment of lumbar degenerative diseases. It has less trauma and lower incidence of paraspinal muscle denervation.

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