The Journal of Practical Medicine ›› 2024, Vol. 40 ›› Issue (23): 3411-3418.doi: 10.3969/j.issn.1006-5725.2024.23.021

• Reviews • Previous Articles    

Research progress on chorioamnionitis and related neonatal diseases

Binghui LI1,Qiong MENG2   

  1. *.Graduate School of Guangdong Medical University,Zhanjiang 524002,Guangdong,China
  • Received:2024-08-27 Online:2024-12-10 Published:2024-12-16

Abstract:

Chorioamnionitis (CAM) refers to an inflammatory condition resulting from pathogen infection of the chorion, amnion, and decidua of the placenta. CAM is associated with preterm birth and an increased risk of adverse outcomes in neonates, including respiratory distress syndrome, bronchopulmonary dysplasia, and elevated perinatal mortality rates. Therefore, early identification, diagnosis, and treatment of CAM are crucial for optimizing therapeutic success in pregnant women and newborns while enhancing the quality of life and disease prognosis for neonates. This review aims to elucidate the correlation between CAM and neonatal diseases as well as provide insights into current prevention strategies and treatment approaches to offer novel clinical perspectives for improved management of CAM?related newborns.

Key words: chorioamnionitis, premature, septicemia of newborn, respiratory distress syndrome of newborn, broncho-pulmonary dysplasia, necrotizing enterocolitis, brain damage

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