实用医学杂志 ›› 2021, Vol. 37 ›› Issue (14): 1842-1845.doi: 10.3969/j.issn.1006⁃5725.2021.14.014

• 临床研究 • 上一篇    下一篇

子宫动脉栓塞术对子宫瘢痕妊娠患者卵巢功能的影响

李涛1, 谢志江2 ,成艳梅1 ,黄晓青2, 王春丽1, 杨新顺3, 张莉华1   

  1. 邯郸市中心医院1 妇科,3 介入科(河北邯郸 056001);2 邯郸市第一医院妇科(河北邯郸 056004)

  • 出版日期:2021-07-25 发布日期:2021-07-25
  • 通讯作者: 张莉华 E⁃mail:litao23litao23@126.com
  • 基金资助:

    2019年邯郸市科技专项计划项目(编号:19422083009⁃10)

Effect of uterine artery embolization on ovarian function in patients with uterine scar pregnancy

LI Tao*, XIE Zhijiang,CHENG Yanmei,HUANG Xiaoqing,WANG Chunli,YANG Xinshun,ZHANG Lihua.   

  1. Department of Gynecology,Handan Central Hospital,Handan 056001,China 

  • Online:2021-07-25 Published:2021-07-25
  • Contact: ZHANG Lihua E⁃mail:litao23litao23@126.com

摘要:

目的 探讨子宫动脉栓塞术对子宫瘢痕妊娠治疗后患者卵巢功能的影响。方法 收集 2012 1 月至 2016 12 月在邯郸市中心医院就诊年龄<40 岁的子宫瘢痕妊娠患者,随机分为子宫动脉 栓塞术组(研究组)和其他方法治疗组(对照组),每组各92例。术后随访3年,定期监测两组患者的月经周 期长度、促卵泡生成素(FSH)、雌二醇(E2)、卵巢窦状卵泡数,并进行统计学分析。结果 子宫动脉栓塞 组中月经周期、FSH、E2、卵巢窦狀卵泡数在治疗结束的第6个月分别为(30.12 ± 3.05)d、(5.10 ± 1.08)IU/L 55.00 ± 11.07)pg/mL、(5.89 ± 1.47)个,第 12 个月分别为(29.97 ± 1.98)d、(5.24 ± 1.14)IU/L、(58.35 ± 12.23)pg/mL、(5.65 ± 1.67)个,第 24 个月分别为(30.17 ± 1.73)d、(5.43 ± 1.25)IU/L、(57.67 ± 10.87)pg/mL 5.51 ± 1.77)个,第36个月分别为(29.78 ± 2.1)d、(5.42 ± 1.29)IU/L、(59.00 ± 12.07)pg/mL、(5.61 ± 1.65)个, 各时间段比较差异无统计学意义(均 P > 0.05)。结论 子宫动脉栓塞术治疗子宫瘢痕妊娠与其它治疗方 法比较不会引起患者3年内的卵巢功能及月经周期的变化。

关键词:

子宫动脉栓塞术, 子宫瘢痕妊娠, 月经周期, 促卵泡生成素, 卵巢窦状卵泡数

Abstract:

Objective To investigate the effect of uterine artery embolization on ovarian function of patients with scar pregnancy. Methods From January 2012 to December 2016,patients with uterine scar pregnancy aged less than 40 years in Handan central hospital were randomized into the uterine artery embolization group (study Group)and other methods treatment group(control group),92 cases in each group. The patients were followed up for 3 years. The menstrual cycle length,follicle stimulating hormone(FSH),estradiol(E2)and the number of ovarian antral follicles of the two groups were regularly monitored and analyzed. Result In UAE group the number of menstrual cycle,FSH,E2 and ovarian antral follicles were(30.12 ± 3.05)days,(5.10 ± 1.08)IU/L 55.00 ± 11.07)pg/mL and(5.89 ± 1.47)in the 6th month,(29.97 ± 1.98)days,(5.24 ± 1.14)IU/L,(58.35 ± 12.23)pg/mL and(5.65 ± 1.67)in the 12th month,(30.17 ± 1.73)days,(5.43 ± 1.25)IU/L,(57.67 ± 10.87)pg/mL and(5.51 ± 1.67 in the 24th month,and(29.78 ± 2.1)days,(5.42 ± 1.29)IU/L,(59.00 ± 12.07)pg/mL and(5.61 ± 1.65)in the 36th month after treatment,respectively. There was no significant difference in each period (all P > 0.05). Conclusion Uterine artery embolization in the treatment of scar pregnancy and other treatment methods will not cause ovarian function and menstrual cycle changes in 3 years.

Key words:

uterine artery embolization, uterine scar pregnancy, menstrual cycle, follicle stimulating hormone, number of antral follicles in ovary