关键词: 妊娠合并结核病, 筛查, 诊断, 治疗, 专家共识

Abstract:

Pregnancy complicated by tuberculosis refers to the development of tuberculosis during pregnancy or pregnancy in women of childbearing age who have not fully recovered from tuberculosis. Clinically， pregnancy complicated by tuberculosis is not an uncommon condition. According to the World Health Organization （WHO）， approximately 200 000 pregnant women develop active tuberculosis annually， and the majority of them are from high-burden countries. With the extensive application of in vitro fertilization-embryo transfer （IVF-ET）， the number of patients with pregnancy complicated by disseminated tuberculosis has increased significantly. In recent years， numerous studies have confirmed that early diagnosis and standardized treatment of tuberculosis during pregnancy can notably improve maternal and infant outcomes. In contrast， delayed treatment may result in severe forms of the disease， such as hematogenous disseminated pulmonary tuberculosis or tuberculous meningitis. Owing to ethical concerns， it is challenging to carry out large-scale randomized controlled trials， which leads to a shortage of corresponding evidence-based medical data. To further standardize the clinical diagnosis and treatment of pregnancy complicated by tuberculosis， the Jiangxi Branch of the National Clinical Research Center for Infectious Diseases， the Tuberculosis Society of Jiangxi Medical Association， and the Nanchang Medical College Innovative Team for the Diagnosis and Treatment of Refractory Tuberculosis have assembled experts to deliberate and formulate this consensus. This consensus integrates the latest research progress from both domestic and international sources， with the aim of offering systematic guidance for clinical practice.

Key words: tuberculosis in pregnancy, screening, diagnosis, treatment, expert consensus