实用医学杂志 ›› 2023, Vol. 39 ›› Issue (4): 499-504.doi: 10.3969/j.issn.1006⁃5725.2023.04.020

• 中医药现代化 • 上一篇    下一篇

不同频率重复经颅磁刺激联合补阳还五汤对气虚血瘀型卒中患者运动功能的疗效观察 

黄婷婷 吴海科 练梦结 杨轩    

  1. 佛山市中医院脑病科(广东佛山528000)

  • 出版日期:2023-02-25 发布日期:2023-02-25
  • 基金资助:
    佛山市自筹经费类科技创新项目(医学类科学攻关)(编号:2220001004983)

Therapeutic effect of rTMS of different frequency combined with Buyang Huanwu Decoction on motor function in stroke patients with qi deficiency and blood stasis

HUANG Tingting,WU Haike,LIAN Mengjie, YANG Xuan.   

  1. Department of Encephalopathy,Foshan Hospital of Traditional Chinese Medicine,Foshan 528000 China

  • Online:2023-02-25 Published:2023-02-25

摘要:

目的 通过探讨不同频率重复经颅磁刺激(rTMS)联合补阳还五汤对气虚血瘀型脑卒中患 者运动功能的疗效,希望能够发现一种恢复脑卒中患者肢体运动功能的有效治疗方法。方法 纳入气虚 血瘀型脑卒中患者 120 例,将其分为中药组 30 例、低频 rTMS(1 Hz)+高频 rTMS(10 Hz)+中药组 30 例、高频 10 Hz)+中药 30 例、低频(1 Hz)+中药组 30 例,观察并分析以上各组患者治疗后在肢体康复情况、rTMS 联合中药治疗取得的临床疗效、日常活动的改善。采用 Fugl⁃Meyer 运动评定量表(FMA)评定 4 组患者 治疗前后的肢体运动功能,对4组中医疗效进行对比,采用ADL(改良Barthel 指数)评定量表评估治疗前后 日常活动的改善。结果 治疗后,4 组患者的 FMA 值、Barthel 指数较治疗前改善(P < 0.01),其中高频+ +中药治疗组疗效更为明显(P < 0.01)。结论 高频(10 Hz)+低频(1 Hz)rTMS 通过双重作用模式, 改变以往单纯高频或低频的模式,调节两个半球之间的失衡状态,并联合补阳还五汤治疗,作为治疗脑 卒中的一种新型的无痛无创康复治疗手段,改善卒中后偏瘫患者运动功能和日常生活,具有重要的临 床应用价值。

关键词: 脑卒中,  , 重复经颅磁刺激,  , 运动功能,  , 补阳还五汤

Abstract:

Objective This study aims to explore the effect of repetitive transcranial magnetic stimulation (rTMS)with different frequencies combined with Buyang Huanwu Decoction on the motor function of patients with stroke of qi deficiency and blood stasis type,trying to find an effective therapy for restoring the limb motor function of stroke patients. Methods A total of 120 patients with subacute stroke of qi deficiency and blood stasis type were enrolled and divided into Traditional Chinese Medicine(TCM)treatment group(n = 30),low frequency rTMS (1 Hz)+ high frequency rTMS(10 Hz)+ TCM treatment group(n = 30),high frequency(10 Hz)+ TCM treatment group(n = 30),and low frequency(1 Hz)+ TCM treatment group(n = 30). The rehabilitation of limbs,clinical efficacy of rTMS combined with TCM,and the improvement of daily activities were observed and analyzed. The Fugl⁃Meyer Motor Rating Scale(FMA)was used to evaluate the limb motor function of the patients in the four groups before and after treatment,and the TCM efficacy of the four groups was compared. The ADL(Modified Barthel Index)was used to evaluate the improvement of daily activities before and after treatment. Results After treatment,the FMA value and Barthel index of the four groups were improved compared with those before treatment (all P < 0.01). The effect of high frequency(10 Hz)+ low frequency(1 Hz)+ TCM treatment group was more significant compared with other groups(P < 0.01). Conclusion rTMS combined with TCM with different frequen⁃ cies can improve moderate⁃severe motor function after stroke. High frequency(10 Hz)+ low frequency(1 Hz rTMS changes the previous simple high frequency or low frequency mode to adjust the imbalance between the two hemispheres through the dual mode of action. Combined with Buyang Huanwu decoction,it is a new painless and non⁃invasive rehabilitation therapy for stroke patients and it can improve their motor function and daily life. It is of value for clinical application.

Key words:

stroke, repetitive transcranial magnetic stimulation, motor function, Buyang Huanwu Decoction