实用医学杂志 ›› 2021, Vol. 37 ›› Issue (13): 1727-1731.doi: 10.3969/j.issn.1006⁃5725.2021.13.017

• 临床研究 • 上一篇    下一篇

免充气经腋窝入路全腔镜下甲状腺手术对喉返神经功能的影响

黄能为, 易茂林, 单华静, 梅俊    

  1. 黄冈市中心医院甲乳外科(湖北黄冈 438000 

  • 出版日期:2021-07-10 发布日期:2021-07-10
  • 通讯作者: 单华静 E⁃mail:krmpg1@163.com
  • 基金资助:

    2019 年黄冈市科技局一般项目子课题(编号:XQYF2019000009)

Impact of total endoscopic thyroid surgery via air ⁃ free transaxillary approach on function of recurrent laryngeal nerve 

HUANG Nengwei,YI Maolin,SHAN Huajing,MEI Jun.   

  1. Department of Thyroid and Breast Sur⁃ gery,Huanggang Central Hospital,Huanggang 438000,China 

  • Online:2021-07-10 Published:2021-07-10
  • Contact: SHAN Huajing E⁃mail:krmpg1@163.com

摘要:

目的 探讨免充气经腋窝入路全腔镜下甲状腺手术对喉返神经(recurrent laryngeal nerve RLN)功能的影响。方法 选取符合纳入和排除标准的患者 300 例,根据手术方案不同分为腔镜组与开放 组,每组 150 例。腔镜组患者行免充气经腋窝入路全腔镜下甲状腺手术治疗,开放组行经颈前切开开放手 术治疗。比较 2 组患者的手术情况及术后恢复情况。Cox 比例风险回归模型分析甲状腺手术中发生 RLN 损伤的影响因素。结果 与开放组相比,腔镜组手术时间延长,术中出血量减少,术后引流液总量增加, 术后住院时间缩短;术后24、48 h,腔镜组患者VAS评分均较低,切口美容满意度评分均较高;术后1周腔镜 组患者的声带病变(χ2 = 15.153,P < 0.001)、嗓音障碍和吞咽功能障碍的发生率(χ2 = 12.837,P < 0.001)均 较低,差异均具有统计学意义(P < 0.05)。行免充气经腋窝入路全腔镜下甲状腺手术和恶性肿瘤是甲状 腺手术中发生 RLN 损伤的独立危险因素(P < 0.05)。结论 免充气经腋窝入路全腔镜下甲状腺手术可有 效提高患者术后生活质量,值得临床推广使用。

关键词:

免充气经腋窝入路, 全腔镜, 甲状腺手术, 喉返神经, 嗓音及吞咽功能

Abstract:

Objective To explore the impact of total endoscopic thyroid surgery via air⁃free transaxillary approach on function of recurrent laryngeal nerve(RLN). Methods A total of 300 patients met the criteria for inclusion and exclusion were divided into endoscopy group(n = 150)and open group(n = 150). The patients in the endoscopy group were treated with total endoscopic thyroidectomy via air⁃free transaxillary approach,while those in the open group received open surgery through anterior cervical incision. The surgical situation and postoperative recovery in the two groups were compared. Cox proportional hazard regression model was used to analyze the influ⁃ encing factors of occurring intraoperative RLN injury. Results As compared with the open group,the endoscopy group had longer surgical duration,less intraoperative blood loss,more postoperative drainage and shorter postop⁃ erative hospital stay,and it had lower VAS score and higher satisfaction score on the cosmetic incision 24 and 48 hours after operation. One week after operation,the incidences of vocal cord lesions(χ2 = 15.153,P < 0.001), dysphonia and dysphagia(χ2 = 12.837,P < 0.001)in the endoscope group were significantly lower than those in the control group(P < 0.05). Total endoscopic thyroid surgery via air⁃free transaxillary approach and malignant tumors were the key risk factors for intraoperative RLN injury. Conclusions Total endoscopic thyroid surgery via air⁃free transaxillary approach can effectively improve the postoperative quality of life in patients and is worthy of clinical application.

Key words:

air ?free transaxillary approach, total endoscopy, thyroid surgery, recurrent laryngeal nerve, voice and swallowing function