实用医学杂志 ›› 2022, Vol. 38 ›› Issue (23): 2957-2961.doi: 10.3969/j.issn.1006⁃5725.2022.23.012

• 临床研究 • 上一篇    下一篇

超高龄急性梗阻性化脓性胆管炎急诊经内镜逆行胰胆管造影术治疗的有效性及安全性分析 

曹立军 黄应文 贺学强 莫春荣 熊红 周先宝 卢水焕 王林 罗燕英 蒋世芳    

  1. 中国人民解放军联勤保障部队第九二四医院消化科(广西桂林541002)

  • 出版日期:2022-12-10 发布日期:2022-12-10
  • 通讯作者: 贺学强 E⁃mail:sgyclj1000@126.com
  • 基金资助:
    广西壮族自治区卫生健康委员会自筹经费科研课题(编号:Z20210383);桂林市技术应用与推广计划项目(编号:2020011209⁃3)

Efficacy and safety of emergency endoscopic retrograde cholangiopancreatography in super elderly patients with acute obstructive suppurative cholangitis

CAO Lijun,HUANG Yingwen,HE Xueqiang,MO Chunrong, XIONG Hong,ZHOU Xianbao,LU Shuihuan,WANG Lin,LUO Yanying,JIANG Shifang.   

  1. Department of Gastroen⁃ terology,No. 924 Hospital,Joint Logistics Support Force of the People′s Liberation Army of China,Guilin 541002 China

  • Online:2022-12-10 Published:2022-12-10
  • Contact: HE Xueqiang E⁃mail:sgyclj1000@126.com

摘要:

目的 探讨急诊经内镜逆行胰胆管造影术(endoscopic retrograde cholangio⁃pancreatography ERCP)治疗超高龄(≥ 85 岁)急性梗阻性化脓性胆管炎(acute obstructive suppurativecholangitis,AOSC)患者 的临床疗效及安全性。方法 回顾性分析中国人民解放军联勤保障部队第九二四医院 2019 1 1 2021 12 31 日接受急诊 ERCP 治疗超高龄 AOSC 患者(观察组 36 例)的临床资料,并与同期< 85 接受急诊 ERCP 治疗 AOSC 患者的临床资料作为对照(对照组 79 例),比较两组间 ERCP 操作的难度及结 果、术后并发症发生率及其严重程度和临床疗效。结果 观察组中 4 级难度操作例次为 41.46%,明显高 于对照组的 28.43%,两组比较差异有统计学意义(P < 0.05),观察组 ERCP 操作成功率为 85.37%,对照组 操作成功率为 90.20%,两组间操作成功率比较差异无统计学意义(P > 0.05);两组患者 ERCP 术后总的并 发症发生率为 9.86%,其中观察组术后并发症的发生率为 12.20%,高于对照组的 8.82%,但两组间术后总 的并发症比较差异无统计学意义(P > 0.05);术后急性胰腺炎、胆管感染、穿孔发生率两组比较差异均无 统计学意义(P > 0.05),观察组中迟发性出血发生率为 4.88%,高于对照组的 0.98%,差异有统计学意义 P < 0.05);两组间并发症严重程度比较差异均无统计学意义(P > 0.05)。观察组中 ERCP 治疗总有效率 86.11%,对照组为 89.87%,两组比较差异无统计学意义(P > 0.05)。结论 在多学科协作综合治疗的前 提下,急诊ERCP 治疗超高龄AOSC 患者疗效显著,安全可靠,值得临床推广。

关键词:

急性梗阻性化脓性胆管炎, 经内镜逆行胰胆管造影术, 急诊, 超高龄, 疗效, 全性

Abstract:

Objective To investigate the clinical efficacy and safety of emergency endoscopic retrograde cholangiopancreatography(ERCP)in the treatment of super elderly(≥ 85 years old)patients with acute obstruc⁃ tive suppurative cholangitis(AOSC). Methods The clinical data of super elderly AOSC patients(36 cases in the observation group)and AOSC patients(< 85)(79 cases in the control group)treated by ERCP in No. 924 Hospital Joint Logistics Support Force of the People′ s Liberation Army of China from January 1,2019 to December 31 2021 were retrospectively analyzed. The difficulty and results of ERCP,the incidence and severity of postoperative complications and clinical efficacy were compared between the two groups. Results In the observation group,the percentage of operations with level⁃4 difficulty was 41.46%,significantly higher than 28.43% in the control group showing significant difference(P < 0.05). The success rate of ERCP in the observation group was 85.37% and that in the control group 90.20%,and there was no statistical difference between the two groups(P > 0.05). The total incidence of complications after ERCP in the two groups was 9.86%. The incidence of postoperative complications in the observation group was 12.20%,higher than 8.82% in the control group,but there was no significant differencebetween the two groups(P > 0.05). There was no significant difference in the incidence of postoperative acute pan⁃ creatitis,bile duct infection and perforation between the two groups(P > 0.05). The incidence of delayed bleeding in the observation group was 4.88%,which was higher than 0.98% in the control group(P < 0.05);There was no significant difference in the severity of complications between the two groups(P > 0.05). The total effective rate of ERCP was 86.11% in the observation group and 89.87% in the control group,indicating no significant difference (P > 0.05). Conclusion With multidisciplinary collaboration,ERCP is effective,safe and reliable in the treat⁃ ment of super elderly AOSC patients,which is worthy of clinical promotion.

Key words: acute obstructive suppurative cholangitis,  , endoscopic retrograde cholangiopancreatography,  , emergency treatment,  , super aged,  , curative effect,  , security