关键词:

纵向弛豫时间, 横向弛豫成像, 磁共振, 细胞外容积分数, 急性心肌梗死

Abstract:

Objective To explore T1，T2 mapping and extracellular volume diagnostic value in patients with acute myocardial infarction. Methods 24 patients with acute myocardial infarction were performed T1，T2 mapping sequence and delayed perfusion examination by a Siemens 1.5 T Aera MRI scanner. The images were input to the syng MR D13 post⁃processing workstation，manually drawn the area of interest in the delayed⁃enhanced segment ，and then the T1 values before and after，T2 Values and reinforcement of area of interest and the blood pool were calculated. With Separate the unreinforced section did not strengthen the area for the control group，the same method was used to calculate the T1 values，T2 values and blood pool T1 values. The extracellular fractions were calculated for both groups. T ⁃test and the ROC curve were used to compare the differences between the two groups（P < 0.05）. Results The initial T1 value（1 320.0 ± 28.4）ms in the delayed enhancement was larger than that in the Separate the unreinforced areas（1 196.8 ± 27.0 ）ms（P < 0.05）. The value of T1 in the delayed enhancement region was declining more obvious than that in the enhancement region. The extracellular volume fraction were（38.7 ± 2.1）% and（24.8 ± 2.5）% respectively（P < 0.05）. The area under the ROC curve of each parameter was 0.812，0.840，0.875，0.819，and it has good sensitivity，specificity and accuracy. From the ROC curve，it can be seen that the diagnostic efficiency of ECV for myocardial infarction is higher than that of other parameters. Conclusion T1，T2 mapping and ECV have a high value in identifying and quantifying acute myocar⁃ dial infarction. 

Key words:

T1 mapping, T2 mapping, magnetic resonance, extracellular volume, acute myocar?ditis infarction ,