实用医学杂志 ›› 2022, Vol. 38 ›› Issue (15): 1856-1859.doi: 10.3969/j.issn.1006⁃5725.2022.15.002

• 专家笔谈 • 上一篇    下一篇

宫颈癌的免疫治疗:精准医学的到来

张颖 吴月玲    

  1. 广东医科大学附属医院妇产医学中心(广东湛江524001)

  • 出版日期:2022-08-10 发布日期:2022-08-10
  • 基金资助:
    国家自然科学基金青年基金项目(编号:81302246)

Immunotherapy incervical cancer:The advent of precision medicine

ZHANG Ying,WU Yueling.   

  1. Department of Obstetrics and Gynecology,Affiliated Hospital of Guangdong Medical University,Zhanjiang 524001,China

  • Online:2022-08-10 Published:2022-08-10

摘要:

宫颈癌是全球女性的第四大常见癌症,但目前常规的治疗手段对晚期及复发转移性宫颈癌 患者的治疗效果十分有限。近年来的研究表明,在宫颈癌中靶向免疫系统的各种治疗方法取得了显著成 效。因此本文将结合国内外宫颈癌免疫治疗的相关研究,对宫颈癌免疫治疗的机制、应用、现状及困境进 行探讨,旨在为宫颈癌的治疗提供一些新方向。

关键词:

宫颈癌, 免疫治疗, PD?1/PD?L1, 研究进展

Abstract:

Cervical cancer is the fourth most common cancer in women worldwide,but conventional treat⁃ ments for advanced,recurrent,and metastatic cervical cancer have limited therapeutic effects. Recent studies have show that remarkable effects have been achieved in various therapies targeting the immune system in cervical can⁃ cer. The article investigates the mechanism underlying the immunological treatment of cervical cancer,the applica⁃ tion of the treatment method,the status quo,as well as the dilemma faced by the treatment method,with the goal of providing some new directions for the treatment of cervical cancer.

Key words:

cervical cancer, immunotherapy, PD?1/PD?L1, research progress