实用医学杂志 ›› 2022, Vol. 38 ›› Issue (15): 1851-1855.doi: 10.3969/j.issn.1006⁃5725.2022.15.001

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咳嗽变异性哮喘与嗜酸粒细胞性支气管炎表型与疗程研究进展 

陈颖 黄俊文 杨淑銮 彭显如 王燕红 赵海金   

  1. 南方医科大学南方医院呼吸与危重症医学科慢性气道疾病实验室(广州 510515)

  • 出版日期:2022-08-10 发布日期:2022-08-10
  • 通讯作者: 赵海金 E⁃mail:zhjin@smu.edu.cn
  • 基金资助:
    国家自然科学基金项目(编号:81770033,81900027,82070030);广州市科技计划项目(编号:201804010069)

Study of the Phenotype and course of treatment of cough variant asthma and eosinophil bronchitis

CHEN Ying,HUANG Junwen,YANG Shuluan,PENG Xianru,WANG Yanhong,ZHAO Haijin.   

  1. Laboratory of Chronic Air⁃ way Diseases,Department of Respiratory and Critical Care Medicine,Nanfang Hospital,Southern Medical Universi⁃ ty,Guangzhou 510515,China 

  • Online:2022-08-10 Published:2022-08-10
  • Contact: Zhao Haijin E⁃mail:zhjin@smu.edu.cn

摘要:


Abstract:

Cough variant asthma(CVA)and eosinophilic bronchitis(EB)are the most common causes of chronic cough. CVA patients are mainly characterized by airway hyperresponsiveness,while EB patients are mainly characterized by eosinophilic airway inflammation and normal lung function. The principal treatment of two diseases is inhaling corticosteroids,which can significantly improve the symptoms and prognosis of these two diseases. However,the association between the duration of ICS treatment and disease progression remains unclear,and there are also diversities in various guidelines. This article aimed at elaborating the different phenotypes and prognosis of CVA and EB,and analyzing the influence factors of the duration of ICS treatments on the prognosis of the diseases. 

Key words:

cough variant asthma, eosinophilic bronchitis, course of treatment, prognosis