实用医学杂志 ›› 2022, Vol. 38 ›› Issue (5): 547-551.doi: 10.3969/j.issn.1006⁃5725.2022.05.005

• 专题报道 • 上一篇    下一篇

Catalyst HD 调强放疗摆位精度的研究光学体表引导发泡胶固定乳腺癌

方键蓝 方涌文 刘镖水 肖亮杰 王宇留 郭旋 何振宇 林承光 姚文燕   

  1. 华南国家肿瘤实验室,中山大学肿瘤防治中心(广州 510060)

  • 出版日期:2022-03-10 发布日期:2022-03-10
  • 通讯作者: 姚文燕 E⁃mail:yaowy@sysucc.org.cn
  • 基金资助:
    国家自然科学基金(编号:81803050,81872459);广东省自然科学基金(编号:2018A030313666);广东省医学科学技术研
    究基金项目(编号:A2020621,A2020516)

Accuracy of immobilization with polyurethane in breast cancer radiotherapy fixed on Catalyst HD optical surface imaging

FANG Jianlan,FANG Yongwen,LIU Biaoshui,XIAO Liangjie,WANG Yuliu,GUO Xuan,HE Zhenyu,LIN Chengguang,YAO Wenyan.   

  1. South China National Cancer Laboratory,Sun Yat⁃sen University Cancer Center,Guangzhou 510060,China 

  • Online:2022-03-10 Published:2022-03-10
  • Contact: YAO Wenyan E⁃mail:yaowy@sysucc.org.cn

摘要:

目的 探讨光学体表成像在发泡胶固定的保乳调强放疗中的辅助摆位功能及其观察区域 对摆位精度的影响。方法 选择 2020 5 月至 2021 7 月在中山大学肿瘤防治中心接受调强放射治疗的乳腺癌患者 34 例。每次治疗前按照体表标记线摆位后,利用光学体表监测系统(C⁃RAD Catalyst HD 辅助校正摆位,最后使用锥形束 CT(Cone Beam CT,CBCT)进行体位验证。按照光学体表监测感兴趣区域 region of interest,ROI)分单患侧 ROI 与双侧 ROI,记录按标记线摆位后的治疗床床值、Catalyst HD 校正后的治疗床床值及CBCT验证后的体位误差数据。将按体表标记线摆位误差与Catalyst HD 校正摆位误差、单 患侧ROI摆位误差与双侧ROI摆位误差进行t检验分析。结果 体表标记线摆位与光学体表辅助摆位在左 右、头脚、腹背方向的摆位误差取绝对值后分别为(2.21 ± 2.14)、(2.46 ± 2.22)、(3.33 ± 2.43)mm 和(1.42 ± 0.99)、(1.31 ± 0.86)、(1.38 ± 1.06)mm,t 值为(LR:-3.473;SI:-4.895;AP:-3.438),均 P < 0.05。单患侧 ROI 和双侧ROI 在左右、头脚、腹背方向三维线性误差分别为(1.59 ± 1.23)、(1.41 ± 1.02)、(1.50 ± 0.93)mm 和(1.71 ± 1.22)、(1.89 ± 1.29)、(1.31 ± 1.71)mm;三维旋转误差分别为[Rtn:(0.53 ± 0.49)°;Roll:(0.77 ± 0.75)°;Pitch:(0.71 ± 0.68)°]和[Rtn:(0.45 ± 0.49)°;Roll:(0.95 ± 0.75)°;Pitch:(0.71 ± 0.69)°],其 AP 以及 Roll P < 0.05,t 值为(AP:0.005;Roll:0.003)。结论 Catalyst HD 可以提高发泡胶固定乳腺癌保乳术后 调强放疗摆位精度,在选择光学体表监测系统监测的感兴趣区域时建议选择双侧ROI。

关键词: 乳腺癌,  , 调强放射治疗,  , 光学体表监测系统,  , 摆位误差

Abstract:

Objective To investigate the auxiliary positioning function of optical body surface imaging in styrofoam⁃fixed breast⁃conserving intensity⁃modulated radiotherapy and the influence of observation area on the posi⁃ tioning. Methods A total of 34 breast cancer patients who received intensity⁃modulated radiation therapy in Sun Yat⁃sen University Cancer Center from May 2020 to July 2021 were selected. The position was set according to the marking line of the body surface,and then corrected by the optical body surface monitoring system(C ⁃RAD Catalyst HD),finally the position was verified by cone beam CT(Cone Beam CT,CBCT). The region of interest (ROI)in C⁃RAD Catalyst HD was divided into single⁃affected ROI and bilateral ROI. The treatment bed value after positioning according to the marking line,and Catalyst HD correction were recorded separately,and the set⁃up errors by CBCT were also recorded. The set⁃up errors according to the marking line of the body surface with the set⁃ up errors of Catalyst HD,the set⁃up errors of the single⁃affected side ROI with the set⁃up errors of the bilateral ROI were analyzed by t test. Results The set⁃up errors by the marking line of the body surface and C⁃RAD Catalyst HD in the left and right,head⁃foot,and abdominal⁃back directions were(2.21 ± 2.14),(2.46 ± 2.22),(3.33 ± 2.43)mm and(1.42 ± 0.99),(1.31 ± 0.86),(1.38 ± 1.06)mm respectively(LR:t = -3.473,SI:t = -4.95,AP t = -3.438,all P < 0.05). The three⁃dimensional linear errors of single⁃affected ROI and bilateral ROI in the left⁃ right,head⁃foot,and abdominal⁃back directions were(1.59 ± 1.23),(1.41 ± 1.02),(1.50 ± 0.93)mm and(1.71± 1.22),(1.89 ± 1.29),(1.31 ± 1.71)mm respectively;three ⁃dimensional rotation errors were[Rtn:(0.53 ± 0.49)°,Roll:(0.77 ± 0.75)°,Pitch:(0.71 ± 0.68)°]and[Rtn:(0.45 ± 0.49)°,Roll:(0.95 ± 0.75)°,Pitch 0.71 ± 0.69)°]respectively(AP:t = 0.005,Roll:t = 0.003,P < 0.05). Conclusion Catalyst HD can improve the positioning accuracy of intensity ⁃modulated radiotherapy after breast ⁃conserving breast cancer with assisted styrofoam fixation. It is recommended to choose bilateral ROI when selecting the region of interest monitored by the Catalyst HD.

Key words:

breast cancer, intensity?modulated radiotherapy, optical body surface monitoring system, set?up error