Objective To study the TCM syndrome types，constitution，and related risk factors of HR⁃HPV infection in the uterine cervix，to provide a clinical basis for its prevention and treatment in TCM. Methods The distribution of TCM syndrome types and constitution in patients with cervical HR⁃HPV infection was studied using epidemiological survey methods. Then investigate the relationship between them. Finally，using multivariate Logistic regression analysisto analyse the risk factors related to cervical HR⁃HPV infection. Results This study surveyed 782 people，309 of whom had cervical HR⁃HPV infection，for an overall infection rate of 39.51%. The HR⁃HPV infection rate follows a U⁃shaped distribution based on age. In the infection group，the syndrome of dampness⁃heat due to spleen deficiency was most commonly seen（50.48%，156/309），the TCM constitution types were mainly dampness ⁃ heat constitution（25.89%，80/309）and yang deficiency constitution（17.48%，54/309）. There were significant positive correlations between syndrome of dampness ⁃ heat due to spleen deficiency and dampness ⁃ heat constitution，kidney ⁃yang deficiency syndrome and yang ⁃deficiency constitution，kidney ⁃yin deficiency syndrome and yin⁃deficiency constitution，as well as dampness⁃toxin accumulation syndrome and Phlegm⁃dampness constitu⁃ tion（P < 0.01）. The age range of 20 ~ 39 years，the number of abortions > 2，the number of parturitions > 2，and the dampness ⁃ heat constitution were all independent risk factors for cervical HR ⁃HPV infection （P < 0.05）， while the balanced constitution was a protective factor against cervical HR ⁃HPV infection（P < 0.05）. Conclusion Multiple factors influence HR ⁃HPV infection in the uterine cervix. Clinical work should include identifying the constitution，disease，and TCM syndrome types，as well as taking early interventions against the relevant risk factors， in order to prevent disease before it starts，avoid changes in the disease，and prevent recurrence in the prognosis.