Objective To understand the prevalence of post⁃stroke depression in China by using a meta⁃ analysis. Methods After searching the databases including CNKI，Wangfang，VIP，and Pubmed，we collected the relevant literature on the prevalence of post ⁃ stroke depression in China before February 28，2021. The Stata 11.0 software was used for meta⁃analysis. Results A total of 50 articles were included，with a total sample size of 22 822 persons. The prevalence of post⁃stroke depression in China was 34.9%（95%CI：3.17% ~ 38.1%）. A sub⁃ group analysis showed that the prevalence of female was higher than that of male，and the prevalence of recurrent patients was higher than that of incipient patients，the differences were statistically significant（P < 0.05）. There were no significant differences in marital status，education level，age，residential region，survey year，stroke types and stroke location. Conclusions The prevalence of post ⁃ stroke depression is higher in China. Clinicians should identify patients with post⁃stroke depression as early as possible，and carry out proper treatment and inter⁃ vention.