Osbjective To investigate the effect of pre⁃hospital delay on cardiac function after primary intervention for acute anterior wall myocardial infarction. Methods Fifty ⁃ seven patients with acute anterior wall myocardial infarction who received primary interventions in our hospital from June 2018 to March 2019 were divided into a long⁃delayed group and a short⁃delayed group according to the pre⁃hospital time. The two groups were compared in terms of cardiac function and global Longitudinal Strain⁃average GLS⁃AVG on the second day and 1 week after the intervention as well as GLS⁃AVG 6 months after intervention. Results There were no significant differences in LVEDD，LVEDVI and LVESVI on the second day between the two groups（P > 0.05）. LVEF on the second day was significantly different as well（P = 0.02）. One week after the operation，there was no significant difference in LVEDD，but LVEDVI and LVESVI were significantly lower in the short ⁃ delayed group than in the long⁃delayed group，and LVEF was significantly higher than in the long⁃delayed group（P < 0.05）. There was a statistically difference between the two groups（P = 0.046）in GLS⁃AVG. During the 6⁃month follow⁃up，there was still significant difference in the cardiac function index between them（P < 0.05）. Conclusion Reducing the pre⁃ hospital delay and revascularization as soon as possible can improve the left ventricular systolic function in patients with acute anterior wall myocardial infarction within 1 week and 6 month