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Predictive value of cervical sagittal parameters and prevertebral soft tissue swelling for dysphagia after anterior cervical spine surgery
Received date: 2026-04-23
Online published: 2026-08-05
Objective To investigate the value of cervical sagittal parameters and the degree of prevertebral soft tissue swelling in predicting dysphagia following Anterior Cervical Spine Surgery (ACSS). Methods Clinical data of 262 patients with cervical spondylosis who were scheduled to undergo ACSS at the hospital from January 2021 to December 2023 were retrospectively collected. All patients were closely monitored for 48 hours post-operatively and then assigned to either a dysphagia group (n = 127) or a non-dysphagia group (n = 135) based on the development of dysphagia within 48 hours. The clinical data, cervical sagittal parameters, and the degree of prevertebral soft tissue swelling were compared between the two groups. Multivariable logistic regression analysis was employed to identify the factors associated with dysphagia after ACSS. Receiver Operating Characteristic (ROC) curves were plotted to assess the predictive value of each factor for post-ACSS dysphagia, and a nomogram model was constructed. Results Multivariable logistic regression analysis demonstrated that TIS, TIA, and NT were independent protective factors against dysphagia following ACSS. In contrast, C2-7 SVA and the degree of prevertebral soft tissue swelling were identified as independent risk factors (P < 0.05). The combined prediction utilizing TIS, C2-7 SVA, TIA, NT, and the degree of prevertebral soft tissue swelling exhibited a higher predictive value compared to any individual parameter (ZTIS-combined = 5.848, ZC2-7 SVA-combined = 5.384, ZTIA-combined = 6.708, ZNT-combined = 5.848, Zdegree of prevertebral soft tissue swelling-combined = 6.643, P < 0.05). The nomogram indicated that the predictive performance of the model was in line with the observed outcomes. The area under the ROC curve (AUC) was 0.84 (0.75 - 0.92) for the training set and 0.83 (0.74 - 0.92) for the validation set, suggesting good predictive performance. Moreover, the model showed a high net benefit across probability thresholds ranging from 50% to 90%. Conclusion Cervical sagittal parameters, when combined with the degree of prevertebral soft tissue swelling, demonstrated good predictive performance for postoperative dysphagia after ACSS and may offer a theoretical basis for the clinical screening of high-risk individuals.
Yongbo AN , Ziqiang LU , Zhiqian ZHANG , Qian CHEN , Song LIN , Lei LI . Predictive value of cervical sagittal parameters and prevertebral soft tissue swelling for dysphagia after anterior cervical spine surgery[J]. The Journal of Practical Medicine, 2026 , 42(14) : 2603 -2612 . DOI: 10.3969/j.issn.1006-5725.2026.14.013
| [1] | 王益,徐彬,陈杨达豪,等. 微创内镜辅助下颈椎前路减压融合术治疗神经根型颈椎病的疗效[J]. 实用医学杂志, 2024, 40(20): 2880-2887. doi: 10.3969/j.issn.1006-5725.2024.20.011 . |
| [2] | 赵文生,李孝林,彭昌华,等. 颈椎前路术后吞咽困难危险因素的meta分析[J]. 海南医学院学报, 2024, 30(11): 850-860. doi: 10.13210/j.cnki.jhmu.20230815.001 . |
| [3] | 陈波,黄天宇,杨林,等. 颈椎前路术后吞咽困难危险因素的Meta分析[J]. 中国脊柱脊髓杂志, 2023, 33(11): 1011-1022. doi: 10.3969/j.issn.1004-406X.2023.11.07 . |
| [4] | 晏蓉,王慧文,李雪丹,等. 颈椎前路术后患者吞咽困难管理的证据总结[J]. 护理学报, 2022, 29(4): 40-45. doi: 10.16460/j.issn1008-9969.2022.04.040 . |
| [5] | 倪励斌,陆逊,夏威夷,等. 枕颈融合术后吞咽困难评估及预测方法的研究进展[J]. 中华骨科杂志, 2024, 44(1): 53-57. doi: 10.3760/cma.j.cn121113- 20230917- 00177 . |
| [6] | 沈健,杜怡斌. 双节段ACDF术后邻近节段退变与颈椎矢状位参数的相关性研究[J]. 颈腰痛杂志, 2024, 45(2): 370-374. doi: 10.3969/j.issn.1005-7234. 2024.02. 037 . |
| [7] | GHAZI SHERBAF F, SAIR H I, SHAKOOR D, et al. DECT in Detection of Vertebral Fracture-associated Bone Marrow Edema: A Systematic Review and Meta-Analysis with Emphasis on Technical and Imaging Interpretation Parameters[J]. Radiology, 2021, 300(1):110-119. doi: 10.1148/radiol.2021203624 . |
| [8] | 唐冰之,胡剑锋,李晓辉. 实用骨科学[M]. 长春: 吉林科学技术出版社, 2019. |
| [9] | 古远莉,麦卓恒,王海铃,等. 颈椎旋提手法对颈型颈椎病患者疼痛、颈椎矢状位参数的改善作用观察[J]. 广州中医药大学学报, 2024, 41(8): 2062-2068. doi: 10.13359/j.cnki.gzxbtcm. 2024.08.018 . |
| [10] | DAI L Y. Significance of prevertebral soft tissue measurement in cervical spine injuries[J]. Eur J Radiol, 2004, 51(1): 73-76. doi: 10.1016/s0720-048x(03)00142-6 . |
| [11] | 任耀民,区国集. 颈椎前路手术术后吞咽困难的影响因素与预防[J]. 临床骨科杂志, 2025, 28(1): 141-145. doi: 10.3969/j.issn.1008-0287. 2025.01. 044 . |
| [12] | 田雪丰,吕俊桥,尉哲铭,等. 颈前路手术治疗颈椎病的有限元研究进展[J]. 医用生物力学, 2024, 39(4): 768-774. doi: 10.16156/j.1004-7220.2024.04.029 . |
| [13] | 殷若恒,刘加伟,蒋伟宇,等. 前路减压融合术治疗颈椎后纵韧带骨化症的研究进展[J]. 中国脊柱脊髓杂志, 2024, 34(1): 77-82. doi:10.3969/j.issn.1004-406X.2024. 01.11 . |
| [14] | NACHALON Y. Anterior cervical spine surgery and dysphagia[J]. Curr Opin Otolaryngol Head Neck Surg, 2022, 30(6): 417-421. doi: 10.1097/MOO. 0000000000000845 . |
| [15] | ALENTADO V J, BISSON E F, POTTS E A. Dysphagia after cervical spine surgery: A review of risk factors and preventative measures[J]. J Neurosurg Spine, 2022, 38(3): 382-388. doi: 10.3171/2022.11.SPINE221247 . |
| [16] | 于杰,陶晓晖. 颈椎曲度变化与颈椎前路或后路术后吞咽困难的关系[J]. 山东医药, 2021, 61(25): 23-26. doi: 10.3969/j.issn.1002-266X.2021.25.006 . |
| [17] | ZHU C, WANG L N, CHEN T Y, et al. Sequential sagittal alignment changes in the cervical spine after occipitocervical fusion[J]. World J Clin Cases, 2022, 10(4): 1172-1181. doi: 10.12998/wjcc.v10.i4.1172 . |
| [18] | XIE R, LIU J, WANG M, et al. Realistic long-term dysphagia rates after anterior cervical discectomy with fusion: Is there a correlation with postoperative sagittal alignment and lordosis at a minimum 2-year follow-up [J]. J Neurosurg Spine, 2022, 37(5): 767-775. doi: 10.3171/2022.4.SPINE211086 . |
| [19] | 史淑芳,郭明霞,王晶晶,等. 颈椎前路手术患者吞咽困难风险预测模型的构建及验证[J]. 护理学杂志, 2025, 40(23): 25-29. doi: 10.3870/j.issn.1001-4152.2025. 23.025 . |
| [20] | ADAM B E, K?L?? O, BOZCAN S, et al. Pharyngeal perforations after anterior cervical spinal procedures: A systematic review[J]. Heliyon, 2024, 11(1):e41466. doi: 10.1016/j.heliyon.2024. e41466 . |
| [21] | USHIRO K, WATANABE Y, KISHIMOTO Y, et al. Complications including dysphagia following transoral non-robotic surgery for pharyngeal and laryngeal squamous cell carcinoma: A retrospective multicenter study[J]. Auris Nasus Larynx, 2024, 51(3): 575-582. doi: 10.1016/j.anl.2024.03.005 . |
| [22] | 陈斌,吴涛,王刚,等. 单节段颈椎病ACDF结合内固定术后吞咽困难的相关因素分析[J]. 中国骨与关节损伤杂志, 2022, 37(1): 39-41. doi: 10.7531/j.issn.1672-9935.2022.01.011 . |
| [23] | TATTER C, EL-HAJJ V G, FLETCHER-SANDERSJ?? A, et al. Radiographic measurements for the prediction of dysphagia after occipitocervical fusion: A systematic review[J]. Acta Neurochir, 2023, 165(5): 1161-1170. doi: 10.1007/s00701- 023-05509-6 . |
| [24] | 黄懿,秦志勇,马迅,等. 颈椎前路融合术后吞咽困难危险因素的研究进展[J]. 中华老年多器官疾病杂志, 2021, 20(7): 556-560. doi: 10.11915/j.issn.1671-5403. 2021.07.116 . |
| [25] | BAKER J F. Analysis of sagittal thoracic inlet measures in relation to anterior access to the cervicothoracic junction[J]. Global Spine J, 2023, 13(3): 705-712. doi: 10.1177/21925682211005730 . |
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