Chronic Disease Control

A randomized controlled study on shock wave therapy for triceps surae spasm in different positions

  • Guixiong CHEN ,
  • Xin LIU ,
  • Fanqiang LI ,
  • Danxian CAI ,
  • Zhengtao ZHENG ,
  • Xiaopeng GAN ,
  • Wei LIU ,
  • Kangling WANG
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  • 1.Department of Rehabilitation Medicine,Zhujiang Hospital,Southern Medical University,Guangzhou 510282,Guangdong,China
    2.Department of Rehabilitation Medicine,the Fifth Affiliated Hospital of Sun Yat?sen University,Zhuhai 519000,Guangdong,China
    3.Department of Rehabilitation Medicine,GuangZhou Red Cross Hospital of Jinan University,Guangzhou 510240,Guangdong,China

Received date: 2025-11-28

  Online published: 2026-03-09

Abstract

Objective To compare the clinical efficacy of radial extracorporeal shock wave therapy (rESWT) applied with the ankle in different positions for treating triceps surae spasticity after stroke, and to provide evidence for optimizing treatment protocols. Methods A prospective, randomized, single-blind (assessor-blinded), controlled design was employed. A total of 58 patients admitted to the hospital between June 2023 and December 2024 were enrolled and randomly assigned to either the experimental group (n = 29, ankle dorsiflexion position) or the control group (n = 29, ankle relaxation position). Both groups received conventional rehabilitation therapy combined with extracorporeal shock wave treatment. Assessments were conducted at four time points: before treatment initiation (T0), on the final day of treatment (T1), at 2 weeks post-treatment (T2), and at 4 weeks post-treatment (T3). The outcome measures included the Composite Spasticity Scale (CSS) for the ankle, 10-Meter Walk Test time (10MWT), step frequency, the Modified Ashworth Scale (MAS), passive range of motion (PROM) of the ankle, and the Fugl-Meyer Assessment for lower extremity motor function (FMA-L). Results The comparative analysis of intervention effects between the experimental and control groups revealed the following key findings: (1)CSS scores decreased significantly over time, with the experimental group showing markedly lower scores than the control group at both mid-term (T2) and late-term (T3) assessments (P < 0.01), and a greater overall improvement (5.65 points vs. 3.17 points, P = 0.003). (2)The 10MWT results demonstrated a consistent improving trend in both groups, although the experimental group performed significantly better than the control group at T2P < 0.01), with a more pronounced overall improvement (7.76 s vs. 6.38 s). (3)Step frequency increased over time, with the experimental group exhibiting higher values than the control group at both T2 and T3P < 0.05), and a greater magnitude of improvement (15.41 steps/min vs. 11.31 steps/min). (4)MAS scores indicated that spasticity relief in the experimental group was superior to that in the control group during the early and mid-term phases (T1, T2) (P < 0.01); however, the control group showed lower scores at T3P < 0.05). (5)PROM assessment revealed that ankle dorsiflexion range of motion improvement in the experimental group was significantly better than that in the control group at all time points (all P < 0.001), with a greater overall increase (7.65° vs. 4.76°). (6)FMA-L scores similarly demonstrated that motor function in the experimental group was superior to that in the control group at all assessed time points (all P < 0.001), with a larger overall improvement (1.62 points vs. 0.55 points). Conclusions rESWT combined with conventional rehabilitation effectively alleviates ankle spasticity and improves gait and motor function in post-stroke patients. Administering rESWT with the ankle in a dorsiflexed position yields superior therapeutic effects on a comprehensive set of functional outcomes compared to a relaxed ankle position. Therefore, the dorsiflexion position is recommended as the preferred posture for clinical application of rESWT in this patient population.

Cite this article

Guixiong CHEN , Xin LIU , Fanqiang LI , Danxian CAI , Zhengtao ZHENG , Xiaopeng GAN , Wei LIU , Kangling WANG . A randomized controlled study on shock wave therapy for triceps surae spasm in different positions[J]. The Journal of Practical Medicine, 2026 , 42(5) : 838 -845 . DOI: 10.3969/j.issn.1006-5725.2026.05.015

References

[1] 《中国脑卒中防治报告2021》编写组.《中国脑卒中防治报告2021》概要[J]. 中国脑血管病杂志,2023,20(11):783-793.doi:103969/jissn1672-5921202311009 .
[2] GBD 2021 Stroke Risk Factor Collaborators. Global, regional, and national burden of stroke and its risk factors, 1990-2021: A systematic analysis for the Global Burden of Disease Study 2021[J]. Lancet Neurol,2024,23(10):973-1003. doi: 10.1016/S1474-4422(24)00369-7 .
[3] LENG Y, ZHANG W, M A J, et al. Prevalence and Risk Factors for Spasticity After Stroke: A Systematic Review and Meta-Analysis[J]. Front Neurol, 2021, 11: 616097.doi:10.3389/fneur.2020.616097 .
[4] YANG E, LEW H L, OZCAKAR L, et al. Recent Advances in the Treatment of Spasticity: Extracorporeal Shock Wave Therapy[J]. J Clin Med, 2021, 10(20): 4723.doi:10.3390/jcm10204723 .
[5] AFZAL B, NOOR R, MUMTAZ N, et al. Effects of extracorporeal shock wave therapy on spasticity, walking and quality of life in poststroke lower limb spasticity: A systematic review and meta-analysis[J]. Int J Neurosci, 2024, 134(12):1503-1517. doi: 10.1080/00207454.2023.2271164 .
[6] CHAVAN R, KAMBLE N, KUTHE C, et al. On Mechanical Behavior and Characterization of Soft Tissues[J]. Biomed Eng Comput Biol, 2024, 15:11795972241294115. doi: 10.1177/11795972241294115 .
[7] FINNI T, DE BRITO FONTANA H, MAAS H. Force transmission and interactions between synergistic muscles[J]. J Biomech, 2023, 152:111575. doi: 10.1016/j.jbiomech.2023.111575 .
[8] YUAN Z, LUO J, CHENG Q F, et al. Clinical efficacy of ultrasound-guided stellate ganglion block combined with extracorporeal shock wave therapy on limb spasticity in patients with ischemic stroke[J]. BMC Neurol, 2023, 23(1):349. doi:10.1186/s12883-023-03391-4 .
[9] 梁豪君,贾海光,朱俊宇,等. 中国骨肌疾病体外冲击波疗法指南(2023年版)[J]. 中国医学前沿杂志(电子版),2023,15(9):1-20.doi:10.12037/YXQY.2023.09-01 .
[10] LIANG J H, JIA H G, ZHU J Y, et al. Chinese guidelines for extracorporeal shock wave therapy for bone and muscle diseases(2023 edition)[J]. Chinese J Front Med Sci, 2023, 15( 9):1-20.doi:10.12037/YXQY.2023.09-01 .
[11] 江剑华,沈仁泽,邱斐,等. 发散式冲击波联合痉挛肌电刺激治疗脑卒中偏瘫患者肱二头肌痉挛的效果[J]. 实用医学杂志, 2025, 41(4): 529-535. doi:10.3969/j.issn.1006-5725. 2025. 04.010 .
[12] 罗伟, 刘春雷, 熊英, 等. 针刺经筋结点对痉挛型偏瘫患者踝关节痉挛的影响[J]. 上海针灸杂志, 2021, 40(3): 319-323. doi:10.13460/j.issn.1005-0957.2021.03.0319 .
[13] 魏天祺, 罗家麒, 李紫娟, 等. 基于丰富环境的增强现实训练对脑卒中步行功能的影响[J]. 中国康复理论与实践, 2023, 29(12):1439-1445.doi:10.3969/j.issn.1006-9771.2023.12. 008 .
[14] BEARD J, WILLIAMS G, KAHN M, et al. The Modified Ashworth and Modified Tardieu Scales differ in their classification of lower limb spasticity[J]. Clin Rehabil, 2025, 39(6):761-769. doi: 10.1177/02692155251337306 .
[15] KWAG Y, PARK D. Effects of a plantar fascia stretching on ankle passive range of motion, balance, gait, and ankle stability in patients with chronic stroke: A randomized controlled study[J]. Top Stroke Rehabil, 2025, 32(2):109-118. doi: 10.1080/10749357.2024.2448928 .
[16] HUANG H, SU X, ZHENG B, et al. Effect and optimal exercise prescription of robot-assisted gait training on lower extremity motor function in stroke patients: A network meta-analysis[J]. Neurol Sci, 2025, 46(3):1151-1167. doi: 10.1007/s10072-024-07780-6 .
[17] SUPUTTITADA A. Emerging theory of sensitization in post-stroke muscle spasticity[J]. Front Rehabil Sci, 2023, 4: 1169087. doi:10.3389/fresc.2023.1169087 .
[18] SCHADING-SASSENHAUSEN S, DIETZ V, FREUND P. Effect of corticospinal and reticulospinal tract damage on spastic muscle tone and mobility: A retrospective observational MRI study[J]. EBio Med, 2025 118:105824. doi: 10.1016/j.ebiom. 2025. 105824 .
[19] 李友华,孙凡,林玉莲,等. 触发点体外冲击波联合肩周类固醇注射对原发性冻结肩患者恢复质量的影响[J]. 实用医学杂志, 2025, 41(9): 1387-1393.doi: 10.3969/j.issn.1006-5725. 2025.09.017 .
[20] CHAWLA S T, SHAHAN J, SOUTIPAN N, et al. Radial Type Low-Intensity Extracorporeal Shockwave Therapy Enhances Penile Microvascular Perfusion in an Aging Rat Model: A Novel Interventional Strategy to Treat Erectile Dysfunction[J]. World J Mens Health, 2025, 43(2):396-406. doi: 10.5534/wjmh. 240032 .
[21] ZIMMERMANN H B, MACINTOSH B R, PUPO J D. The Relationship Between Length and Active Force for Submaximal Skeletal Muscle Contractions: A Review[J]. Sports Med, 2025, 55(1):37-47. doi: 10.1007/s40279-024-02140-y .
[22] GIANGRANDE A, CERONE G L, BOTTER A, et al. Volitional muscle activation intensifies neuronal processing of proprioceptive afference in the primary sensorimotor cortex: An EEG study[J]. J Neurophysiol, 2024, 131(1):28-37. doi: 10.1152/jn. 00340.2023 .
[23] HAROON M, KLEIN-NULEND J, BAKKER A D, et al. Myofiber stretch induces tensile and shear deformation of muscle stem cells in their native niche[J]. Biophys J, 2021, 120(13):2665-2678. doi: 10.1016/j.bpj.2021.05.021 .
[24] YU X S, LEVINE J T, PONS J L. Modulation of motor unit recruitment threshold and common synaptic inputs in triceps surae muscles: effects of ankle position[J]. J Appl Physiol, 2025, 138(6):1638-1650. doi: 10.1152/japplphysiol.00029.2025 .
[25] NAGAI A, MARUMOTO K, OHATA K, et al. Effects of ankle dorsiflexion training on anticipatory postural adjustments during gait initiation in patients with Parkinson's disease[J]. Gait Posture, 2025, 117:109-114. doi: 10.1016/j.gaitpost.2024.12.015 .
[26] ANEGAWA K, KAWANISHI K, NAKAMURA M, et al. Tibial nerve dynamics during ankle dorsiflexion: The relationship between stiffness and excursion of the tibial nerve[J]. J Biomech, 2023, 155:111646. doi: 10.1016/j.jbiomech.2023.111646 .
[27] BOROVIKOV Y S, TISHKOVA M V, AVROVA S V, et al. The Twisting and Untwisting of Actin and Tropomyosin Filaments Are Involved in the Molecular Mechanisms of Muscle Contraction, and Their Disruption Can Result in Muscle Disorders[J]. Int J Mol Sci, 2025, 26(14):6705. doi: 10.3390/ijms26146705 .
[28] GORKO B, SIWANOWICZ I, CLOSE K, et al. Motor neurons generate pose-targeted movements via proprioceptive sculpting[J]. Nature, 2024, 628(8008):596-603. doi: 10.1038/s41586-024-07222-5 .
[29] ZHAO Y, ZHANG T, WANG S, et al. Development of a 3D active movement extent discrimination apparatus for testing proprioception at the ankle joint with inversion movements made in plantarflexion[J]. Eur J Sport Sci, 2025, 25(1):e12238. doi: 10.1002/ejsc.12238 .
[30] ROMENI S, LOSANNO E, EMEDOLI D, et al. High-frequency epidural electrical stimulation reduces spasticity and facilitates walking recovery in patients with spinal cord injury[J]. Sci Transl Med, 2025, 17(780):eadp9607. doi: 10.1126/scitranslmed.adp9607 .
[31] FRITH J, ROBINSON L, GIBBON J R, et al. The effect of lower limb strengthening exercise on orthostatic blood pressure and the skeletal muscle pump in older people with orthostatic hypotension[J]. Clin Physiol Funct Imaging, 2024, 44(3):205-210. doi: 10.1111/cpf.12866 .
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