The Journal of Practical Medicine >

2026 , Vol. 42 >Issue 1: 163 - 168

DOI: https://doi.org/10.3969/j.issn.1006-5725.2026.01.022

Reviews

Research progress of the role of adipose-derived mesenchymal stem cells in organ ischemia-reperfusion injury

  • Yuan ZHOU ,
  • Hong ZHANG
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  • 1.Department of Anestheiology，Affiliated Hospital of Zunyi Medical University，Zunyi 563099，Guizhou，China
    2.Key Laboratory of Anesthesia and Organ Protection of the Ministry of Education（In cultivation），Zunyi Medical University，Zunyi 563006，Guizhou，China

Received date: 2025-07-11

  Online published: 2026-01-14

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Abstract

Ischemia/reperfusion injury （IRI） is the cause of various pathological injuries such as ischemic stroke， acute coronary syndrome， and acute lung injury. Mesenchymal stem cells （MSCs） are adult stem cells with the ability to self-renew and differentiate into multiple lineages， and adipose derived mesenchymal stem cells（ADMSCs） have similar functions. The treatment methods of adipose derived mesenchymal stem cells mainly include transplantation and injection of adipose derived mesenchymal stem cells or their secreted exosomes， which can inhibit inflammatory response， resist oxidative stress， promote tissue repair and regeneration， and regulate immune response. They have the potential to be used as a treatment and improve the prognosis of ischemia-reperfusion injury. Therefore， this article focuses on the research progress of the protective effects of adipose derived mesenchymal stem cells in organs such as the heart， brain， lungs， liver， and kidneys.

Key words： ischemia-reperfusion injury; adipose-derives mesenchymal stem cells; research progress

Cite this article

Yuan ZHOU , Hong ZHANG . Research progress of the role of adipose-derived mesenchymal stem cells in organ ischemia-reperfusion injury[J]. The Journal of Practical Medicine, 2026 , 42(1) : 163 -168 . DOI: 10.3969/j.issn.1006-5725.2026.01.022

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