COVID⁃19 is currently a public health problem forall mankind. The spread of the epidemic has severely affected the global economy，health，population，social development and people′s living habits. Although most patients are mostly non ⁃ severe with a good prognosis，a few patients are severeand progress rapidly. There⁃ fore，it is important to explore the progress factors of COVID⁃19 for prediction of out come and adjustment of the treatment strategies. Here we summarizes the factors affecting the prognosis of COVID⁃19.