The Journal of Practical Medicine >
Progress in autologous fat grafting for scar treatment
Received date: 2025-02-26
Online published: 2025-05-20
Scarring is a key issue in plastic surgery research and there are limitations in the clinical outcomes of existing scar treatments. Autologous fat grafting is a new method that has been clinically proven to be effective in the treatment of pathological scarring. Autologous fat grafts contain adipose-derived mesenchymal stem cells and a variety of active factors that can effectively improve the appearance， texture and local symptoms of keloid scars through the mechanisms of immunomodulation of the inflammatory response， pro-angiogenesis， pro-cellular differentiation， extracellular matrix remodelling and resistance to oxidative stress damage， etc. It has the advantages of fewer complications and better therapeutic effect， and is a brand new field of keloid scar， which provides a new therapeutic direction for the keloid scar. The new field of scar treatment provides a new direction for scar treatment. The application and mechanism of autologous fat grafting in keloid scar is now reviewed， with the aim of providing a theoretical basis for the treatment of keloid scar and summarising the progress of its application in keloid scar treatment.
Xifeng AN , Xuan LIAO , Hongwei LIU . Progress in autologous fat grafting for scar treatment[J]. The Journal of Practical Medicine, 2025 , 41(9) : 1425 -1432 . DOI: 10.3969/j.issn.1006-5725.2025.09.022
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