Objective To compare plantar dynamic and static pressure parameters between patients with type 2 diabetes mellitus （T2DM） and those with combined diabetic peripheral neuropathy （DPN）， and to analyze associated factors. Methods A retrospective analysis was conducted on 47 cases in the pure T2DM group and 57 cases in the T2DM combined with DPN group. The plantar dynamic and static pressure parameters， along with relevant clinical data， were recorded for each group. Results Age， BMI， cholesterol， and triglycerides were significantly higher in the combined DPN group compared to the T2DM group （P < 0.05）. The average pressure on both feet and the axial angle of the left foot were also significantly greater in the combined DPN group than in the simple T2DM group （P < 0.05）. A larger axial angle suggests an impact on gait or foot function. Additionally， the forefoot loading ratio， hindfoot loading ratio， and medial?lateral loading ratio of the left foot were all significantly higher in the combined DPN group compared to the simple T2DM group （P < 0.05）. For static pressure parameters， no statistically significant differences were observed between the two groups in terms of foot area， load， maximum pressure， or average pressure （P > 0.05）. Spearman's univariate analysis revealed that plantar dynamic and static maximum pressure， mean pressure， and total plantar pressure area were significantly and positively correlated with BMI and triglycerides. Multiple linear regression analysis indicated that the axial angle of the left foot during dynamic pressure was associated with triglyceride levels （P < 0.05）， the load ratio of the left anterior and posterior foot was related to the duration of diabetes mellitus （P < 0.05）， and the bipedal area， maximal pressure， and mean pressure during static pressure were all associated with BMI. Conclusions Dynamic plantar pressure mean compression， left foot axis angle， and loading ratio had a greater influence on foot function in the combined DPN group compared to the T2DM group alone. Regardless of the presence of DPN， attention should be paid to measuring plantar pressure in patients. early intervention using indicators associated with plantar dynamic and static pressures， such as BMI and triglycerides， can provide a clinical reference for preventing diabetic foot complications.