The Journal of Practical Medicine >

2024 , Vol. 40 >Issue 20: 2929 - 2934

DOI: https://doi.org/10.3969/j.issn.1006-5725.2024.20.018

Investigations

A multicenter population investigation on precancerous lesions of gastric cancer in Lishui District， Nanjing

  • Chunyan NIU ,
  • Xiaoping WANG ,
  • Xiangyang ZHAO ,
  • Jiankang HUANG ,
  • Yue CHEN ,
  • Yongqiang SHI ,
  • Yongqiang SONG ,
  • Hui WANG ,
  • Xinguo WU ,
  • Yongdan BU ,
  • Jijin LI ,
  • Tao TAO ,
  • Jinhua WU ,
  • Changlin XUE ,
  • Fuyu ZHANG ,
  • Jinming YANG ,
  • Chunrong HAN ,
  • Juan YUAN ,
  • Yinling WU ,
  • Hongbing XIONG ,
  • Peng XIAO
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  • Department of Gastroenterology，Nanjing Lishui District Peoples Hospital，Nanjing 211200，Jiangsu，China

Received date: 2023-08-30

  Online published: 2024-11-05

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Abstract

Objective By population survey， to explore the epidemiological characteristics of gastric precancerous lesions in Lishui District of Nanjing and provide objective basis for the prevention and treatment of early gastric cancer. Methods From July 2021 to December 2022， 21 977 patients who received endoscopy and/or 13C-UBT in Lishui District People's Hospital and 6 medical community units in Nanjing City were retrospectively analyzed for demography characteristics， detection rate of gastric precancerous lesions， and H. Pylori infection rate. Results （1） 590 cases of gastric precancerous lesions were detected （detection rate 2.68%）； （2） The total detection rate of precancerous lesions and three pathological types in males were all higher than those in females （all P < 0.001）； （3） The minimum age for the total detection rate of precancerous lesions in males and the minimum age for each pathological type were lower than in females （P < 0.001， 0.009， 0.005， 0.002）； （4） The population total H. pylori infection rate was 23.10%， the H. pylori infection rate in patients with precancerous lesions was higher than that in non-precancerous lesions （P < 0.001）， both H. pylori infection rate of male and female in precancerous lesions were all higher than those of non-precancerous lesions of the same sex （all P < 0.001）， in addition， the H. pylori infection rate of male whether in precancerous or non-precancerous lesions was higher than that of female （all P < 0.001）； （5） The precancerous lesions detection rate in male， female， and the overall age range of 20 ~ 29 to 70 ~ 79 years is positively correlated with age growth （P < 0.001）， and rapidly decreases after the age of 79， the of H. pylori infection rate was also positively correlated with age growth （P < 0.001）， and the trend of age change （P < 0.001） was parallel to the precancerous lesions detection rate. Conclusions The detection rate of gastric precancerous lesions in this region is above the average level in China；the total H. pylori infection rate is at a relatively low level in China； the H. pylori infection rate is parallel to the age trend of the detection rate of gastric precancerous lesions， and increases with age.

Key words： early gastric cancer; gastric precancerous lesions; H. pylori; infection rate; Epidemic profile

Cite this article

Chunyan NIU , Xiaoping WANG , Xiangyang ZHAO , Jiankang HUANG , Yue CHEN , Yongqiang SHI , Yongqiang SONG , Hui WANG , Xinguo WU , Yongdan BU , Jijin LI , Tao TAO , Jinhua WU , Changlin XUE , Fuyu ZHANG , Jinming YANG , Chunrong HAN , Juan YUAN , Yinling WU , Hongbing XIONG , Peng XIAO . A multicenter population investigation on precancerous lesions of gastric cancer in Lishui District， Nanjing[J]. The Journal of Practical Medicine, 2024 , 40(20) : 2929 -2934 . DOI: 10.3969/j.issn.1006-5725.2024.20.018

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