The Journal of Practical Medicine >

2024 , Vol. 40 >Issue 19: 2789 - 2795

DOI: https://doi.org/10.3969/j.issn.1006-5725.2024.19.021

Reviews

Research progress on the application of platelet⁃rich fibrin in promoting bone regeneration during maxillary sinus floor lifting surgery

  • Shan′en XIE ,
  • Yan ZHANG ,
  • Guochen WEN ,
  • Hao QU ,
  • Wei. DONG
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  • School of Stomalotogy，North China University of Science and Technology，Tangshan 063210，Hebei，China

Received date: 2024-01-17

  Online published: 2024-10-22

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Abstract

Maxillary sinus floor lifting surgery is a commonly used surgical method in the field of oral implantology to solve the problem of insufficient vertical bone in the posterior maxillary area. It includes internal and external maxillary sinus lifting. Platelet-rich fibrin （PRF）， as a second-generation platelet concentrate， has certain osteoinductive properties and can promote the osteogenic differentiation of mesenchymal stem cells. In maxillary sinus floor lifting surgery， PRF is often mixed with bone grafting materials or used alone， which has great application prospects. Based on current research， the molecular mechanism of PRF promoting osteogenic differentiation of maxillary sinus mucoperiosteal has not been reported in detail， and the application of PRF in maxillary sinus floor lifting surgery is still controversial.This article reviewed the mechanism of PRF in promoting osteogenic differentiation of maxillary sinus mucoperiosteal after maxillary sinus floor lifting surgery， as well as the different application methods of PRF in maxillary sinus floor lifting surgery based on relevant literature， in order to provide a reference for clinicians to rationally use PRF in maxillary sinus floor lifting surgery and furtherly promote the clinical application of PRF.

Key words： maxillary sinus floor lifting surgery; platelet-rich fibrin; bone regeneration; application methods

Cite this article

Shan′en XIE , Yan ZHANG , Guochen WEN , Hao QU , Wei. DONG . Research progress on the application of platelet⁃rich fibrin in promoting bone regeneration during maxillary sinus floor lifting surgery[J]. The Journal of Practical Medicine, 2024 , 40(19) : 2789 -2795 . DOI: 10.3969/j.issn.1006-5725.2024.19.021

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