The Journal of Practical Medicine >
Sarcopenia associated with chronic obstructive pulmonary disease
Received date: 2023-11-29
Online published: 2024-05-15
Sarcopenia is a progressive and systemic skeletal muscle disease and an important extrapulmonary complication of chronic obstructive pulmonary disease （COPD）. Multiple studies have confirmed that COPD patients with sarcopenia have more severe airflow obstruction and emphysema， higher dyspnea index scores， reduced quality of life and exercise capacity， frequent acute exacerbations， and increased mortality. Although sarcopenia has been mentioned as a complication of COPD for many years， current clinical practice has received insufficient attention and insufficient intervention. The main reason is that its pathogenesis is unknown and drug treatment regimens are ineffective. As more and more research has been done on COPD combined with sarcopenia in recent years， this article reviews the current research progress to pay attention to further research and early intervention， including new mechanisms， diagnostic criteria， and drug treatment progress.
Key words： chronic obstructive pulmonary disease; sarcopenia; progress
Shifang YANG , Xinglin GAO , Jing LI , Lupeng. JI . Sarcopenia associated with chronic obstructive pulmonary disease[J]. The Journal of Practical Medicine, 2024 , 40(9) : 1181 -1185 . DOI: 10.3969/j.issn.1006-5725.2024.09.001
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