The Journal of Practical Medicine >

2024 , Vol. 40 >Issue 5: 596 - 600

DOI: https://doi.org/10.3969/j.issn.1006-5725.2024.05.002

Symposiums

The research progress of the actions of mast cells in sepsis

  • Junling WANG ,
  • Mengmeng ZHAN ,
  • Zhaolong ZHANG ,
  • Shaoheng HE ,
  • Bingyu. QIN
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  • Department of Critical Care Medicine，Henan Provincial People's Hospital，Zhengzhou University People's Hospital，Zhengzhou 450003，China
    Allergy and Clinical Immunology Research Centre，the First Affiliated Hospital of Jinzhou Medical University，Jinzhou 121001，China

Received date: 2023-12-01

  Online published: 2024-03-26

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Abstract

Sepsis is a life-threatening organ dysfunction， which is caused by the body's uncontrolled immune response to infection. Tissue masts cells （MC）， derived from blood mast cell progenitors， are one of the classical effector cells in inflammatory response. MC plays an important role in sepsis via secreting a variety of inflammatory mediators and cytokines. Here， we summarized the potential roles of MC in sepsis， which is expected to provide novel ideas for the future research on the novel mechanisms of MC in sepsis.

Key words： sepsis; mast cell; potential roles

Cite this article

Junling WANG , Mengmeng ZHAN , Zhaolong ZHANG , Shaoheng HE , Bingyu. QIN . The research progress of the actions of mast cells in sepsis[J]. The Journal of Practical Medicine, 2024 , 40(5) : 596 -600 . DOI: 10.3969/j.issn.1006-5725.2024.05.002

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