Objective To investigate the effect of cognitive-behavioral intervention under the family-centered care （FCC） model on continuing care of patients after aortic dissection surgery. Methods One hundred and six patients undergoing aortic dissection in the Department of Cardiac Surgery of the hospital from January 2021 to December 2022 were evenly divided into control group and observation group by using random number table method， with 53 cases in each group. The control group was given routine continuing care， and the observation group was treated with continuing care with the cognitive behavior intervention under the FCC mode based on the control group， and both groups intervened for 8 weeks. The control group was treated with routine continuity care， while the observation group received continuity care with cognitive-behavioral intervention based on the FCC model in addition to routine continuing care， with a intervention duration of 8 weeks for both groups. The two groups were compared in terms of blood pressure， body mass index （BMI）， self-care ability （measured using the Self-Care Ability Scale-ESCA）， quality of life （measured using the Short Form-36 Health Survey-SF-36）， and levels of depression and anxiety （measured using the Hospital Anxiety and Depression Scale - HADS） before and after the intervention. Results The level of blood pressure， BMI， and level of depression and anxiety after the intervention were all significantly lower than before the intervention （P < 0.05） and the scores by ESCA and SF-36 were significantly higher than before intervention （P < 0.05）. The blood pressure and BMI in the observation group were both significantly better than in the control group ［（116.47 ± 28.23）mmHg vs. （124.48 ± 29.81）mmHg and （25.33 ± 1.11）kg/m²vs. 26.18 ± 1.35）kg/m²， t = 7.193， 2.454， P < 0.01， respectively］. The scores of self-care ability and quality of life in the observation group were higher than in the control group ［（121.15 ± 29.69） vs. （106.68 ± 24.71） and （67.92 ± 13.69） vs. （60.81±10.77）， t = 8.243， 7.436， P < 0.01， respectively］. The scores of depression and anxiety in the observation group were significantly lower than in the control group［（11.07 ± 4.00） vs. （12.20 ± 4.28） and （12.39 ± 3.59） vs. （13.45 ± 4.15）， t = 3.873， 2.852， P < 0.01， respectively］. Conclusion The cognitive-behavioral intervention under the FCC mode can significantly improve blood pressure， BMI， and psychological condition， as well as enhance patients' self-care ability and quality of life， when applied in the continuity of care for patients after aortic dissection. Therefore， it is worth promoting and applying in clinical practice.