The Journal of Practical Medicine >

2024 , Vol. 40 >Issue 2: 248 - 252

DOI: https://doi.org/10.3969/j.issn.1006-5725.2024.02.021

Medical Examination and Clinical Diagnosis

Values of different DIC scoring systems in early diagnosis and prognosis prediction of coagulation dysfunction in sepsis patients

  • Fangmin GENG ,
  • Yuandan HE ,
  • Wenjuan LI ,
  • Qianqian LIU ,
  • Hongwei ZHANG ,
  • Zhangping LU ,
  • Lianhua WEI
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  • Gansu University of Traditional Chinese Medicine，Lanzhou 730000，China

Received date: 2023-08-21

  Online published: 2024-03-06

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Abstract

Objective To evaluate five types of DIC scoring systems based on sepsis patients， to explore the values of different DIC scoring systems in the occurrence and prognosis of DIC in sepsis patients， and to compare the applicability of different DIC scoring systems for sepsis complicated with DIC. Methods Laboratory indexes and clinical data from sepsis patients who had been hospitalized in Gansu Provincial People's Hospital from December 1， 2019 to December 31， 2021 were retrospectively analyzed within 24 hours. Five types of DIC scoring systems were used to score， and the difference of diagnostic rate and discharge outcome in sepsis patients with different severity was compared. The ROC curves of five DIC scoring systems were established to evaluate the accuracy of DIC in sepsis patients. Results The fatality rate of sepsis increased with the severity of sepsis （P < 0.05）. There were statistically significant differences in discharge outcomes between DIC and non-DIC in the five scoring systems （P < 0.05）. JMHW， CDSS and part of ISTH were detected in JAAM cases， while ISTH was detected in non-dominant ISTH cases. ISTH， JAAM， JMHW， CDSS， and non-dominant ISTH5 scoring systems were used to diagnose DIC， and absence of full health restoration and death were 3.0， 3.8， 4.2， 3.9， and 3.0 times higher than non-DIC cases， respectively. Conclusion JAAM scoring system has higher diagnostic rate and sensitivity for adult sepsis. CDSS and JMHW scoring systems are more accurate in predicting the prognosis of sepsis patients.

Key words： sepsis; DIC; scoring systems; diagnostic efficacy

Cite this article

Fangmin GENG , Yuandan HE , Wenjuan LI , Qianqian LIU , Hongwei ZHANG , Zhangping LU , Lianhua WEI . Values of different DIC scoring systems in early diagnosis and prognosis prediction of coagulation dysfunction in sepsis patients[J]. The Journal of Practical Medicine, 2024 , 40(2) : 248 -252 . DOI: 10.3969/j.issn.1006-5725.2024.02.021

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