The Journal of Practical Medicine >

2024 , Vol. 40 >Issue 1: 114 - 118

DOI: https://doi.org/10.3969/j.issn.1006-5725.2024.01.020

Modernization of Traditional Chinese Medicine

Effects of Busheng Huayu Qianggu prescription in elderly patients with osteoporotic lumbar fracture of kidney deficiency and blood stasis type

  • Guodong QIU ,
  • Lei SUN ,
  • Shuihua. XIE
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  • *.Graduate School of Jiangxi University of Traditional Chinese Medicine，Nanchang 330006，China

Received date: 2023-08-14

  Online published: 2024-01-24

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Abstract

Objective To investigate the application value of Bushen Huayu Qianggu prescription in the treatment of senile osteoporotic lumbar fracture with kidney deficiency and blood stasis type. Methods All elderly patients with osteoporotic lumbar fractures of kidney deficiency and blood stasis were treated in our hospital from September 2021 to March 2023 and randomly divided into 68 cases in both groups. The control group was treated with conventional Western medicine， and the observation group was treated with BushengHuayuQiang Gu prescription for 12 weeks. Results Serum D-dimer （D-D）， interleukin-6 （IL-6） and prostaglandin E2 （PGE2） were lower in the observation group than in the control group， and vascular endothelial growth factor （VEGF） and β-endorphin （β-EP） were higher （P < 0.05）； serum osteoprotegerin （OPG） and bone morphogenetic protein-2 （BMP-2） were higher in the observation group （P < 0.05）； total effective rate was as high as 95.59% （65%） （P < 0.05）； bone mineral density （BMD） was higher in the observation group than in the control group after treatment， and the total symptom score and Cobb angle of Chinese medicine were lower （P < 0.05）； the total effective rate of the observation group was as high as 95.59% （65/68）， higher than that of the control groupwhich was 80.88%（55/68）（P < 0.05）. Conclusion Combined treatment with BushenHuayuQianggu prescription can reduce inflammation， regulate bone metabolism， promote bone mineral density and improve clinical efficacy for senily-aged lumbar osteoporotic fracture caused by kidney deficiency and blood stasis.

Key words： Bushen Huayu Qianggu prescription; kidney deficiency and blood stasis type; osteoporotic lumbar fracture

Cite this article

Guodong QIU , Lei SUN , Shuihua. XIE . Effects of Busheng Huayu Qianggu prescription in elderly patients with osteoporotic lumbar fracture of kidney deficiency and blood stasis type[J]. The Journal of Practical Medicine, 2024 , 40(1) : 114 -118 . DOI: 10.3969/j.issn.1006-5725.2024.01.020

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