Reviews

Research progress on relationship between cardiac amyloidosis and atrial fibrillation and its pathogenesis

  • Bo WU ,
  • Hengli LAI ,
  • Guowang SHEN ,
  • Zhenhuan CHEN ,
  • Yuan. LIU
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  • *.Nanchang University Medical College,Nanchang 330000,China
    *.Jiangxi Provincial People′s Hospital,the First Affiliated Hospital of Nanchang Medical college,Nanchang 330000,China

Received date: 2023-06-13

  Online published: 2023-09-27

Abstract

Cardiac amyloidosis (CA) is a myocardial disease caused by extracellular deposition of misfolded amyloid proteins in the myocardium. CA is associated with a higher prevalence of atrial fibrillation (AF), and myocardial amyloid infiltration can contribute to atrial electrical and structural remodeling through hemodynamic changes, increased ventricular wall stress, atrial amyloid deposition, and autonomic dysfunction, leading to the development and progression of AF. At present, the mechanism of CA in the pathogenesis of AF has not been elucidated. Therefore, exploring the relationship between CA and AF and the possible pathogenesis will help to deepen the knowledge of such patients and provide reference for clinical prevention and treatment.

Cite this article

Bo WU , Hengli LAI , Guowang SHEN , Zhenhuan CHEN , Yuan. LIU . Research progress on relationship between cardiac amyloidosis and atrial fibrillation and its pathogenesis[J]. The Journal of Practical Medicine, 2023 , 39(17) : 2277 -2279 . DOI: 10.3969/j.issn.1006-5725.2023.17.022

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