Clinical Research

Application of calcium phosphate mixture PRP reconstruction of necrotic areas for early metaphase osteo⁃necrosis of the femeral head

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  • He′nan University of Traditional Chinese Medicine,Zhengzhou 450003,China

Online published: 2020-12-14

Abstract

Objective The research tried to investigate the reliability of platelet⁃rich plasma compositesβ⁃alcium phosphate for the treatment of early Osteonecrosis of the Femoral Head. Methods 108 patients of earlyOsteonecrosis of the Femoral Head(unilateral lesion)were randomly divided into compound group(52 cases)andcontrol group(56 cases). The control group was treated with osteonecrosis bone scraping,biomaterials β⁃alciumphosphate particles filling and pressing as well as β⁃alcium phosphate columnar ceramic rod implantation. Thecomposite group mixed biomaterials β ⁃alcium phosphate particles to match platelet⁃ich plasma filling andcompression and columnar calcium phosphate ceramic rod implantation. The VAS and Harris scores,imaging evalu⁃ation and quantitative indexes were compared between the two groups. Results Compared with multiple time sitesin 24 months after operation,the implant mineralization and new bone crawling growth replacement in the compos⁃ite group were significantly better than those in the control group(P < 0.05). The VAS and Harris in the compositegroup were also better than those in the control group(F = 30.12,17.88,P<0.05). Conclusion Platelet⁃richplasma composites β⁃alcium phosphate have a reliable advantage in the treatment of early Osteonecrosis of theFemoral Head,which could accelerate the growth and mineralization of new bone crawling,promote the fusion ofcalcium phosphate implants with their own host bone and facilitate functional recovery.


Cite this article

ZHANG Xiao, WANG Shangzeng, ZHANG Yingang, ZHANG Yingjie, LI Yun⁃peng, XU Dayong . Application of calcium phosphate mixture PRP reconstruction of necrotic areas for early metaphase osteo⁃necrosis of the femeral head[J]. The Journal of Practical Medicine, 2020 , 36(22) : 3116 -3120 . DOI: 10.3969/j.issn.1006⁃5725.2020.22.017

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