With the aggravation of social aging，the morbidity and mortality of heart failure are gradually increasing. Therefore，more and more attention has been paid to diverse therapies for the treatment of heart failure all over the world. At the same time，new progress has been made in the treatment of heart failure，and the guidelines for heart failure have also been constantly updated in many countries. At present，angiotensin receptor enkephalin inhibitors，sodium and glucose cotransporter 2 inhibitors，soluble guanylatecyclase activators，iron supplements， recombinant human relaxin⁃2 and cardiac rehabilitation have been proved to benefit patients with heart failure. This article will review the progress in the treatment of heart failure in order to provide reference for clinical treatment.