Abstract:

Objective To analyze the changes of glottic exposure classification and related factors in Pierre Robin sequence pediatric patients after mandibular distraction osteogenesis. Methods Ninety five pediatric patients with Pierre Robin sequence，scheduled for elective mandibular distraction osteogenesis under general anes⁃ thesia in our hospital from 2016 to 2019，were enrolled in this study. The results of Cormack Lehane classification and CT parameters of upper airway were compared before and after mandibular distraction osteogenesis. Pearson correlation analysis was used to evaluate the correlation between CT measurement indexes and Cormack Lehane grading score. Results The Cormack Lehane score and the incidence of glottic exposure difficulty were decreased compared with that before mandibular distraction osteogenesis（P < 0.05），the length of D1，D2，D3，D4，D5， D6，D7，D8，D9，D10，D11 were increased（P < 0.05）；angle 1，angle 2 and angle 5 were increased；angle 3， angle 4 and angle 6 were decreased（P < 0.05）；airway cross⁃sectional area and palatopharyngeal cavity volume at the tip of epiglottis were increased（P < 0.05）. It was negatively correlated with Cormack Lehane classification. Conclusion Preoperative maxillofacial and upper airway CT can play an important role in the judgment of laryngo⁃ scope exposure classification in PRS patients. With the increase of airway cross⁃sectional area and velopharyngeal cavity volume，glottic exposure classification of infants with Pierre Robin sequence sign after mandibular distrac⁃ tion osteogenesis was significantly improved.

Key words:

Pierre Robin syndrome, mandible distraction osteogenesis, upper airway morphology, glottic exposure