两种运动强度规定方法对代谢综合征患者体成分及心肺运动试验指标的影响

doi:10.3969/j.issn.1006-5725.2024.19.003

Abstract

Abstract:

Objective To compare the effects of two exercise intensities on metabolic syndrome （MS）. Methods Forty-nine MS patients hospitalized in Taiyuan Central Hospital from December， 2022 to January 2024 were selected and randomly divided into two groups： a standard group（n = 24） and individual group（n = 25）. All patients underwent cardiopulmonary exercise test （CPET） before and after treatment， collecting major indexes including body parameter， body component， and metabolic indicator for prescribing exercise programs. The standard group was trained with exercise intensity prescribed on heart rate reserve， while the individual group received the exercise with intensity prescribed on ventilatory threshold. Both groups received equal energy consumption exercise intervention with the same exercise frequency for 12 weeks. Results The two groups demonstrated significant improvements in waist circumference （WC）， body mass index （BMI）， body fat related indexes， and systolic blood pressure after intervention （P < 0.05）. The individual group showed significant improvements inWC， BMI and body fat related indexes as compared to the standard group （P < 0.05）. Both groups showed significant improvements in peak oxygen uptake，（PeakVO₂）， peak load power （Peak WR）， peak metabolic equivalent （PeakMets）， and peak respiratory exchange ratio （Peak RER） after intervention （P < 0.05）. The individual group presented significant improvements in peak heart rate （HRpeak）， peak oxygen pulse （Peak VO₂/HR）， and maximum voluntary ventilation （MVV）（P < 0.05） after intervention. Before intervention， the standard group demonstrated significantly higher levels in PeakVO₂ and Peak MET compared to the individual group （P < 0.05）， but after intervention the two groups showed no significant differences in the two indexes. After the intervention， the individual group demonstrated insignificant improvements in all indexes compared to the standard group （P > 0.05）. Conclusions Both exercise prescriptions based on CPET can effectively improve the health-related indicators of MS patients on condition of moderate exercise intensity. However， the program prescribed based on individualized ventilatory threshold shows superiority to the program prescribed based on maximum physiological value in improving these indicators.

Key words: exercise intensity, ventilatory threshold, metabolic syndrome, cardiopulmonary exercise test, exercise prescription

CLC Number:

R589

Ruojiang LIU,Jinmei QIN,Weizhen XUE,Zhi LI,Feng WANG,Xiang ZHANG,Hongyu LIU,Zhiqiang. PEI. Effect of exercise intensity on body components and CPET indexes of MS patients： A comparison of two prescribed programs[J]. The Journal of Practical Medicine, 2024, 40(19): 2678-2684.

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References 34

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	标准化组（n = 24）	个体化组（n = 25）	t/χ²值	P值
年龄/岁	42.42 ± 10.96	44.92 ± 12.21	-0.754	0.454
男/女/（例）	17/7	14/11	1.159	0.282
体质量/kg	91.51 ± 16.80	85.23 ± 15.26	1.371	0.177
身高/cm	170.29 ± 8.25	169.52 ± 7.26	0.348	0.730
BMI/（kg/m²）	31.42 ± 4.47	29.48 ± 3.62	1.666	0.102

指标	标准化组（n = 24）		t值	P值	个体化组（n = 25）		t值	P值	干预前组间		干预后组间
指标	干预前	干预后	t值	P值	干预前	干预后	t值	P值	t值	P值	t值	P值
WC/cm	103.83 ± 9.96	101.81 ± 10.57^?	4.068	< 0.001	98.72 ± 8.42	94.56 ± 9.18^?	5.246	< 0.001	1.943	0.058	2.567	0.014
BMI/（kg/m²）	31.42 ± 4.47	30.76 ± 4.41^?	3.359	0.003	29.49 ± 3.61	28.33 ± 3.45^?	6.009	< 0.001	1.660	0.103	2.153	0.036
SMM/kg	33.69 ± 6.92	33.67 ± 6.84	0.096	0.924	31.51 ± 6.67	31.57 ± 6.44	-0.448	0.658	1.123	0.267	1.106	0.274
FM/kg	31.45 ± 8.79	29.82 ± 9.17^?	3.685	< 0.001	28.64 ± 6.86	25.46 ± 6.49^?	8.064	< 0.001	1.254	0.216	1.926	0.060
PBF/%	34.21 ± 6.07	33.20 ± 6.80^?	2.891	0.008	33.56 ± 5.38	30.75 ± 5.25^?	7.820	< 0.001	0.396	0.694	1.412	0.165
VFA/cm²	142.56 ± 43.26	134.23 ± 44.3^?	3.950	< 0.001	133.89 ± 34.95	116.42 ± 33.79^?	7.096	< 0.001	0.773	0.443	1.586	0.119
TG/（mmol/L）	2.40 ± 1.31	2.20 ± 0.84	0.989	0.333	2.43 ± 1.01	2.27 ± 1.36	0.837	0.411	-0.089	0.929	-0.203	0.840
TC/（mmol/L）	5.10 ± 1.32	5.00 ± 1.60	0.557	0.583	4.54 ± 1.12	4.38 ± 1.41	0.745	0.463	1.613	0.113	1.438	0.157
LDL/（mmol/L）	3.38 ± 1.04	3.23 ± 1.24	1.000	0.328	3.03 ± 0.83	2.82 ± 1.02	1.238	0.228	1.299	0.200	1.272	0.210
HDL/（mmol/L）	1.13 ± 0.17	1.16 ± 0.25	-0.851	0.404	1.01 ± 0.21	1.04 ± 0.24	-0.730	0.473	1.736	0.076	1.787	0.080
SBP/mmHg	128.83 ± 9.33	125.58 ± 7.87^?	2.487	0.021	127.64 ± 11.79	122.32 ± 10.43^?	5.762	< 0.001	0.392	0.697	1.232	0.224
DBP/mmHg	84.46 ± 8.99	83.04 ± 7.64	1.037	0.310	83.04 ± 10.18	79.20 ± 10.34^?	4.398	< 0.001	0.516	0.608	1.475	0.147

CPET指标	标准化组（n = 24）				个体化组（n = 25）				干预前组间		干预后组间
CPET指标	干预前	干预后	t值	P值	干预前	干预后	t值	P值	t值	P值	t值	P值
PeakVO₂/［mL/（min·kg）］	24.88 ± 4.54	28.01 ± 5.95^?	-3.446	0.002	22.20 ± 4.12	26.68 ± 5.68^?	-6.740	< 0.001	2.163	0.036	0.801	0.427
PeakWR/watt	161.50 ± 46.62	184.46 ± 52.65^?	-5.253	< 0.001	139.28 ± 51.46	162.52 ± 52.28^?	-8.216	< 0.001	1.582	0.120	1.463	0.150
PeakMets/MET	7.10 ± 1.29	7.91 ± 1.70^?	-3.161	0.004	6.35 ± 1.17	7.55 ± 1.67^?	-6.226	< 0.001	2.123	0.039	0.760	0.451
HRpeak/bpm	160.17 ± 20.74	162.79 ± 17.67	-1.221	0.234	144.96 ± 23.63	150.04 ± 21.18^?	-3.801	< 0.001	2.390	0.021	2.283	0.027
（PeakVO₂/HR）/（mL/beat）	14.23 ± 3.19	15.07 ± 4.05	-1.813	0.083	13.36 ± 3.34	14.59 ± 4.26^?	-4.226	< 0.001	0.935	0.355	0.403	0.689
PeakRER	1.12 ± 0.07	1.16 ± 0.05^?	-2.948	0.007	1.11 ± 0.07	1.17 ± 0.06^?	-8.094	< 0.001	0.662	0.511	-0.331	0.742
OUES/（mL/logL）	2 575.29 ± 746.67	2 444.11 ± 634.32	0.843	0.408	2 287.04 ± 694.37	2 245.47 ± 667.84	0.800	0.432	1.400	0.168	1.067	0.292
LowestVE/VCO₂	29.63 ± 2.16	29.05 ± 2.59	1.362	0.186	30.18 ± 2.32	29.87 ± 3.05	0.650	0.522	-0.865	0.392	-1.016	0.315
VE/VCO₂ slope	27.35 ± 2.50	26.45 ± 2.16	1.641	0.114	26.8 ± 2.6	27.19 ± 2.11	-0.777	0.445	0.765	0.448	-1.217	0.230
（ΔVO₂/ΔWR）/［mL/（min·W）］	10.71 ± 0.74	10.68 ± 0.96	0.143	0.887	10.58 ± 1.12	10.8 ± 1.05	-1.216	0.236	0.502	0.618	-0.428	0.671
VO₂@VT1/［mL/（min·kg）］	13.39 ± 2.17	13.75 ± 3.08	-0.682	0.502	13.03 ± 1.67	13.54 ± 2.19	-1.792	0.086	0.652	0.518	0.271	0.787
FVC/L	4.03 ± 0.92	3.97 ± 0.84	0.918	0.368	3.61 ± 0.97	3.72 ± 0.99	-2.205	0.037	1.547	0.129	0.956	0.344
MVV/（L/min）	131.27 ± 25.99	132.11 ± 28.69	-0.203	0.841	119.81 ± 26.52	126.49 ± 30.5^?	-2.863	0.009	1.527	0.134	0.664	0.510

变化指标	校正后差值		组别效应
变化指标	标准化组	个体化组	F值	P值	偏η²
PeakVO₂/［mL/（kg·min）］	3.79 ± 0.94	4.74 ± 0.94	0.478	0.494	0.013
PeakWR/watt	22.94 ± 3.78	23.26 ± 3.70	0.004	0.952	0.000
PeakMets/MET	0.80 ± 0.24	1.20 ± 0.23	1.389	0.245	0.029
HRpeak/bpm	3.65 ± 1.60	4.12 ± 1.63	0.040	0.842	0.001
（PeakVO₂/HR）/（mL/beat）	0.77 ± 0.38	1.29 ± 0.37	0.943	0.336	0.020
MVV/（L/min）	1.19 ± 3.42	6.35 ± 3.35	1.133	0.293	0.024

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Effect of exercise intensity on body components and CPET indexes of MS patients： A comparison of two prescribed programs

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