人脐带间充质干细胞在皮肤创面修复中的研究进展

doi:10.3969/j.issn.1006-5725.2025.21.024

Abstract

Abstract:

Mesenchymal stem cells （MSCs） are multipotent stromal cells that possess the capacity for self-renewal and differentiation into multiple cell lineages. Due to the ease of procurement， robust expansion in vitro， the multipotency， they are recognized as a vital source of stem cells in the field of regenerative medicine. MSCs can be isolated from various tissues， including bone marrow， adipose tissue， and umbilical cord. Research indicates that Human umbilical cord mesenchymal stem cells （hUCMSCs） play an effective role in wound healing and tissue regeneration， and can be utilized for the repair of skin wounds. They are also considered to be the most promising seed cells for skin tissue engineering. This review aims to provide an overview of the biological characteristics of hUCMSCs， the mechanisms in promoting skin wound healing， and their clinical applications.

Key words: human umbilical cord mesenchymal stem cells, skin, wound repair

CLC Number:

R751

Xinyu LIU,Mengmeng KONG,Yi FU,Jialin LAI,Jun LI,Jianghua. SUN. The role of human umbilical cord mesenchymal stem cells in skin wound repair： A literature review[J]. The Journal of Practical Medicine, 2025, 41(21): 3462-3466.

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The role of human umbilical cord mesenchymal stem cells in skin wound repair： A literature review

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